Aptamer-based point-of-care devices: Emerging technologies and integration of computational methods

Y Aslan, M Atabay, HK Chowdhury, I Göktürk, Y Saylan… - Biosensors, 2023 - mdpi.com
Recent innovations in point-of-care (POC) diagnostic technologies have paved a critical
road for the improved application of biomedicine through the deployment of accurate and …

Nucleic acid-based wearable and implantable electrochemical sensors

C Ye, H Lukas, M Wang, Y Lee, W Gao - Chemical Society Reviews, 2024 - pubs.rsc.org
The rapid advancements in nucleic acid-based electrochemical sensors for implantable and
wearable applications have marked a significant leap forward in the domain of personal …

Rapid identification and monitoring of multiple bacterial infections using printed nanoarrays

Z Zhang, Y Sun, Y Yang, X Yang, H Wang… - Advanced …, 2023 - Wiley Online Library
Fast and accurate detection of microbial cells in clinical samples is highly valuable but
remains a challenge. Here, a simple, culture‐free diagnostic system is developed for direct …

Active enrichment of nanoparticles for ultra-trace point-of-care COVID-19 detection

Y Luo, M Zhou, C Fan, Y Song, L Wang, T Xu… - Analytical …, 2023 - ACS Publications
Active enrichment can detect nucleic acid at ultra-low concentrations without relatively time-
consuming polymerase chain reaction (PCR), which is an important development direction …

Multiplexed electrochemical assays for clinical applications

M Sharafeldin, JF Rusling - Current opinion in electrochemistry, 2023 - Elsevier
Rapid, accurate diagnoses are central to future efficient healthcare to identify diseases at
early stages, avoid unnecessary treatment, and improve outcomes. Electrochemical …

Pursuing precision in medicine and nutrition: the rise of electrochemical biosensing at the molecular level

S Campuzano, R Barderas, MT Moreno-Casbas… - Analytical and …, 2024 - Springer
In the era that we seek personalization in material things, it is becoming increasingly clear
that the individualized management of medicine and nutrition plays a key role in life …

Reagentless protein-based electrochemical biosensors

SM Silva, M Li, AX Mendes, SE Moulton - Analyst, 2023 - pubs.rsc.org
The creation of reagentless protein-based biosensors that are capable of monitoring
molecular analytes directly in bodily fluids could revolutionize our understanding of biology …

Single‐Response Duplexing of Electrochemical Label‐Free Biosensor from the Same Tag

JNY Costa, GJC Pimentel, JA Poker… - Advanced …, 2024 - Wiley Online Library
Multiplexing is a valuable strategy to boost throughput and improve clinical accuracy.
Exploiting the vertical, meshed design of reproducible and low‐cost ultra‐dense …

DNA Nanomachine-Driven Heterogeneous Quadratic Amplification for Sensitive and Programmable miRNA Profiling

H Shen, G Cui, H Liang, H Yang, M Chen… - Analytical …, 2023 - ACS Publications
Inspired by the molecular crowding effect in biological systems, a novel heterogeneous
quadratic amplification molecular circuit (HEQAC) was developed for sensitive bimodal …

Aptamer–Antibody Chimera Sensors for Sensitive, Rapid, and Reversible Molecular Detection in Complex Samples

D Kong, IAP Thompson, N Maganzini, M Eisenstein… - ACS …, 2024 - ACS Publications
The development of receptors suitable for the continuous detection of analytes in complex,
interferent-rich samples remains challenging. Antibodies are highly sensitive but difficult to …