Basal cell carcinoma (BCC) is the most common skin malignancy, which rarely metastasizes
but has a great ability to infiltrate and invade the surrounding tissues. One of the molecular …

Pancreatic cancer (PAC) is a highly fatal and aggressive type of cancer. Hypoxia is a
common feature of PAC. The aim of this study was to develop a hypoxia status-related …

Ubiquitination-related genes (URGs) exerted a crucial part in a variety of human disease
disorders; however, their association with pancreatic adenocarcinoma (PAAD) had yet to be …

Background Increasing evidence has shown that hypoxia microenvironment relates to tumor
initiation and progression. However, no studies focus on the application of hypoxia …

The dysregulated expression of glycolysis-related genes (GRGs) is closely related to the
occurrence of diverse tumors and regarded as a novel target of tumor therapy. However, the …

Objective Pancreatic ductal adenocarcinoma (PDAC) has high mortality and poor prognosis.
Pyroptosis can influence the prognosis of patients by regulating the proliferation, invasion …

The biology of metastatic pancreatic ductal adenocarcinoma (PDAC) is distinct from that of
the primary tumor due to changes in cell plasticity governed by a distinct transcriptome …

Background Gene mutations play critical roles in tumorigenesis and cancer development.
Our study aimed to screen survival-related mutations and explore a novel gene signature to …

Disulfidptosis, a regulated form of cell death, has been recently reported in cancers
characterized by high SLC7A11 expression, including invasive breast carcinoma, lung …

Background Tumor immune microenvironment (TiME) is prognostically instructive in
Pancreatic adenocarcinoma (PAAD). However, the potential value of TiME-related genes in …