Paradigms of dynamic control of thyroid hormone signaling

AC Bianco, A Dumitrescu, B Gereben… - Endocrine …, 2019 - academic.oup.com
Thyroid hormone (TH) molecules enter cells via membrane transporters and, depending on
the cell type, can be activated (ie, T4 to T3 conversion) or inactivated (ie, T3 to 3, 3′-diiodo-l …

Retinal organoids: a window into human retinal development

M O'Hara-Wright, A Gonzalez-Cordero - Development, 2020 - journals.biologists.com
Retinal development and maturation are orchestrated by a series of interacting signalling
networks that drive the morphogenetic transformation of the anterior developing brain …

A flexible ultrasensitive optoelectronic sensor array for neuromorphic vision systems

QB Zhu, B Li, DD Yang, C Liu, S Feng, ML Chen… - Nature …, 2021 - nature.com
The challenges of developing neuromorphic vision systems inspired by the human eye
come not only from how to recreate the flexibility, sophistication, and adaptability of animal …

Dynamic machine vision with retinomorphic photomemristor-reservoir computing

H Tan, S van Dijken - Nature Communications, 2023 - nature.com
Dynamic machine vision requires recognizing the past and predicting the future of a moving
object based on present vision. Current machine vision systems accomplish this by …

Gate-tunable van der Waals heterostructure for reconfigurable neural network vision sensor

CY Wang, SJ Liang, S Wang, P Wang, Z Li, Z Wang… - Science …, 2020 - science.org
Early processing of visual information takes place in the human retina. Mimicking
neurobiological structures and functionalities of the retina provides a promising pathway to …

A single‐cell transcriptome atlas of the adult human retina

SW Lukowski, CY Lo, AA Sharov, Q Nguyen… - The EMBO …, 2019 - embopress.org
The retina is a specialized neural tissue that senses light and initiates image processing.
Although the functional organization of specific retina cells has been well studied, the …

[HTML][HTML] Human brain organoids assemble functionally integrated bilateral optic vesicles

E Gabriel, W Albanna, G Pasquini, A Ramani… - Cell stem cell, 2021 - cell.com
During embryogenesis, optic vesicles develop from the diencephalon via a multistep
process of organogenesis. Using induced pluripotent stem cell (iPSC)-derived human brain …

Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development

Y Lu, F Shiau, W Yi, S Lu, Q Wu, JD Pearson… - Developmental cell, 2020 - cell.com
The development of single-cell RNA sequencing (scRNA-seq) has allowed high-resolution
analysis of cell-type diversity and transcriptional networks controlling cell-fate specification …

Light-enhanced molecular polarity enabling multispectral color-cognitive memristor for neuromorphic visual system

J Lee, BH Jeong, E Kamaraj, D Kim, H Kim… - Nature …, 2023 - nature.com
An optoelectronic synapse having a multispectral color-discriminating ability is an essential
prerequisite to emulate the human retina for realizing a neuromorphic visual system. Several …

[HTML][HTML] Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids

CM Fligor, SS Lavekar, J Harkin, PK Shields… - Stem Cell Reports, 2021 - cell.com
The development of the visual system involves the coordination of spatial and temporal
events to specify the organization of varied cell types, including the elongation of axons from …