Surfactant protein D in respiratory and non-respiratory diseases

GL Sorensen - Frontiers in medicine, 2018 - frontiersin.org
Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …

Systemic inflammation in chronic obstructive pulmonary disease: may adipose tissue play a role? Review of the literature and future perspectives

R Tkacova - Mediators of inflammation, 2010 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide. Low‐grade systemic inflammation is considered a hallmark of COPD that …

Commentary: Why are children in the same family so different? Non-shared environment three decades later

R Plomin - International journal of epidemiology, 2011 - academic.oup.com
The importance of non-shared environment lay hidden within quantitative genetic studies
since they began nearly a century ago. Quantitative genetic methods, such as twin and …

Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD

DA Lomas, EK Silverman, LD Edwards… - European …, 2009 - publications.ersnet.org
Surfactant protein (SP)-D is a lung-derived protein that has been proposed as a biomarker
for inflammatory lung disease. Serum SP-D was evaluated as a biomarker for components of …

The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease

DD Sin, SFP Man, DD Marciniuk, G Ford… - American journal of …, 2008 - atsjournals.org
Rationale: Small studies have suggested that inhaled corticosteroids can suppress systemic
inflammation in chronic obstructive pulmonary disease (COPD). Objectives: To determine …

[HTML][HTML] Surfactant protein A and surfactant protein D variation in pulmonary disease

GL Sorensen, S Husby, U Holmskov - Immunobiology, 2007 - Elsevier
Surfactant proteins A (SP-A) and D (SP-D) have been implicated in pulmonary innate
immunity. The proteins are host defense lectins, belonging to the collectin family which also …

Surfactant protein D in human lung diseases

D Hartl, M Griese - European journal of clinical investigation, 2006 - Wiley Online Library
The lung is continuously exposed to inhaled pollutants, microbes and allergens. Therefore,
the pulmonary immune system has to defend against harmful pathogens, while an …

Pulmonary and systemic toxicity in rats following inhalation exposure of 3-D printer emissions from acrylonitrile butadiene styrene (ABS) filament

MT Farcas, W McKinney, C Qi, KW Mandler… - Inhalation …, 2020 - Taylor & Francis
Background Fused filament fabrication 3-D printing with acrylonitrile butadiene styrene
(ABS) filament emits ultrafine particulates (UFPs) and volatile organic compounds (VOCs) …

[HTML][HTML] Krebs von den Lungen-6 (KL-6) as a clinical marker for severe COVID-19: A systematic review and meta-analyses

N Naderi, M Rahimzadeh - Virology, 2022 - Elsevier
Abstract Background Krebs von den Lungen-6 (KL-6) is a molecule that is predominantly
expressed by damaged alveolar type II cells, and has been proposed as a marker of COVID …

Circulatory serum Krebs von den Lungen-6 and surfactant protein-D concentrations predict interstitial lung disease progression and mortality

M Rai, A Parthasarathi, NM Beeraka, M Kaleem Ullah… - Cells, 2023 - mdpi.com
There is a need for biomarkers to predict outcomes, including mortality, in interstitial lung
disease (ILD). Krebs von den Lungen-6 (KL-6) and surfactant protein D (SP-D) are …