Abstract The legacy of Gilbert Newton Lewis (1875–1946) pervades the lexicon of chemical
bonding and reactivity. The power of his concept of donor–acceptor bonding is evident in the …

The carbon-carbon bond formation and the functional group transformations are the most
fundamental reactions for the construction of a molecular framework and hence represent a …

In a patent application published in 1972, Baylis and Hillman reported the reaction of
acetaldehyde with ethyl acrylate and acrylonitrile in the presence of catalytic amounts of 1, 4 …

The development of an efficient, asymmetric variant of the Baylis–Hillman reaction for the
synthesis of enantiomerically pure α‐methylene‐β‐hydroxycarbonyl compounds (see …

Accurate calculations are presented on the mechanism of the MBH reaction, focusing on the
reaction between methyl acrylate and benzaldehyde, catalyzed by a tertiary amine. We …

Abstract Das Erbe von Gilbert Newton Lewis (1875–1946) ist im Wörterbuch der
chemischen Bindung und Reaktivität allgegenwärtig. Die Bedeutung seines Konzepts der …

The design of ligands for biological systems to provide increased understanding of function
at a molecular level and to open avenues for therapeutic agents has placed increased …

A practical and efficient set of conditions were developed using stoichiometric base catalyst,
1, 4-diazabicyclo [2, 2, 2] octane (DABCO), and an aqueous medium to overcome problems …

Using reaction rate data collected in aprotic solvents, we have determined that the Baylis−
Hillman rate-determining step is second order in aldehyde and first order in DABCO and …

The Baylis− Hillman reaction, the coupling of an unsaturated carbonyl compound/nitrile with
aldehydes, is a valuable reaction but is limited in its practicality by poor reaction rates. We …