Continuous spermatogenesis in post-pubertal mammals is dependent on spermatogonial
stem cells (SSCs), which balance self-renewing divisions that maintain stem cell pool with …

Treatment of cancer with chemo-or radiotherapy causes reduction of sperm counts often to
azoospermic levels that may persist for several years or be permanent. The time course of …

This review addresses current understanding of the germline stem cell niche unit in
mammalian testes. Spermatogenesis is a classic model of tissue-specific stem cell function …

Spermatogonial stem cells (SSCs) maintain spermatogenesis throughout a man's life and
may have application for treating some cases of male infertility, including those caused by …

Because germline mutations are the source of all evolutionary adaptations and heritable
diseases, characterizing their properties and the rate at which they arise across individuals …

This article will provide an updated review of spermatogonial stem cells and their role in
maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial …

The identity and behavior of mouse spermatogenic stem cells have been a long-standing
focus of interest. In the prevailing" A s model," stem cell function is restricted to singly …

Spermatogenesis is highly orchestrated and involves the differentiation of diploid
spermatogonia into haploid sperm. The process is driven by spermatogonial stem cells …

Spermatogenesis is a complex developmental process that ultimately generates mature
spermatozoa. This process involves a phase of proliferative expansion, meiosis, and …

This review describes the regulation of spermatogenesis taking into consideration the
hypothalamic–pituitary gonadal axis, the male reproductive organs and the endocrine and …