Recent advances in the development of fluorescent probes for γ‐glutamyltranspeptidase

ZY Hu, XY Chen, YS Yang, SJ Wang, ZG Hu… - Coordination Chemistry …, 2024 - Elsevier
Abstract γ-Glutamyltranspeptidase (GGT) plays a significant role in the regulation of cellular
redox homeostasis and other physiological or pathophysiological processes. The over …

Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC

J Liang, F Liu, P Xu, W Shangguan… - Proceedings of the …, 2023 - National Acad Sciences
Trehalose plays a crucial role in the survival and virulence of the deadly human pathogen
Mycobacterium tuberculosis (Mtb). The type I ATP-binding cassette (ABC) transporter LpqY …

From Bench to Clinic: A Nitroreductase Rv3368c-Responsive Cyanine-Based Probe for the Specific Detection of Live Mycobacterium tuberculosis

X Hong, P Geng, N Tian, X Li, M Gao, L Nie… - Analytical …, 2024 - ACS Publications
Tuberculosis (TB), characterized by high mortality and low diagnosis, is caused by a single
pathogen, Mycobacterium tuberculosis (Mtb). Imaging tools that can be used to track Mtb …

Fluorogenic Probes of the Mycobacterial Membrane as Reporters of Antibiotic Action

MG Wuo, CL Dulberger, TC Warner… - Journal of the …, 2024 - ACS Publications
The genus Mycobacterium includes species such as Mycobacterium tuberculosis, which can
cause deadly human diseases. These bacteria have a protective cell envelope that can be …

[HTML][HTML] Photoinactivation of Mycobacterium tuberculosis and Mycobacterium smegmatis by Near-Infrared Radiation Using a Trehalose-Conjugated Heptamethine …

NV Kozobkova, MP Samtsov, AP Lugovski… - International Journal of …, 2024 - mdpi.com
The spread of multidrug-resistant mycobacterium strains requires the development of new
approaches to combat diseases caused by these pathogens. For that, photodynamic …

Modulating and Accelerating Photolysis of Photoactivatable [2.2] Paracyclophane Aryl Azide in Supramolecular Host for Bioimaging

X Qiu, E Pohl, Q Cai, J Seibert, Y Li… - Advanced Functional …, 2024 - Wiley Online Library
Photolysis of aryl azides offers a versatile approach to achieve more sophisticated
functionalization, for instance in the field of chemical biology. In this study, a …

Maltose-Derivatized Fluorescence Turn-On Imaging Probe for Bacteria Detection

SH Liyanage, M Yan - ACS Infectious Diseases, 2023 - ACS Publications
We report a maltose-derivatized fluorescence turn-on imaging probe, Mal-Cz, to detect E.
coli and Staphylococci. The fluorescence turn-on is achieved through an intramolecular C–H …

[HTML][HTML] Click-free imaging of carbohydrate trafficking in live cells using an azido photothermal probe

Q Xia, HA Perera, R Bolarinho, ZA Piskulich, Z Guo… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Real-time tracking of intracellular carbohydrates remains challenging. While click chemistry
allows bio-orthogonal tagging with fluorescent probes, the reaction permanently alters the …

Overview of Small Molecules as Fluorescent Probes of Mycobacterium tuberculosis

K Stavropoulou, IP Papanastasiou - ACS omega, 2024 - ACS Publications
Tuberculosis (TB) remains one of the leading infectious causes of death worldwide.
Detecting and precisely quantifying viable Mycobacterium tuberculosis (M. tuberculosis) is …

Modulating the photolysis of aryl azides in a supramolecular host to develop photoactivatable fluorophores

X Qiu, E Pohl, A Jung, Q Cai, H Su, O Fuhr… - Chemical …, 2024 - pubs.rsc.org
Photolysis of aryl azides is a convenient method to approach more functionalized systems in
chemical biology. Here, we present a set of photoactivatable aryl azides that undergo …