Cardiovascular disease and COPD: dangerous liaisons?

KF Rabe, JR Hurst, S Suissa - European Respiratory Review, 2018 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD)
frequently occur together and their coexistence is associated with worse outcomes than …

The role of acidosis in the pathogenesis of severe forms of COVID-19

YD Nechipurenko, DA Semyonov, IA Lavrinenko… - Biology, 2021 - mdpi.com
Simple Summary Recently, several studies have shown that acidosis, which is increased
acidity in the blood and other body tissues, is often associated with severe COVID-19. In this …

Diagnosis and prediction of COVID-19 severity: can biochemical tests and machine learning be used as prognostic indicators?

A de Fátima Cobre, DP Stremel, GR Noleto… - Computers in biology …, 2021 - Elsevier
Objective This study aimed to implement and evaluate machine learning based-models to
predict COVID-19'diagnosis and disease severity. Methods COVID-19 test samples (positive …

Separating smoking-related diseases using NMR-based metabolomics of exhaled breath condensate

G de Laurentiis, D Paris, D Melck… - Journal of Proteome …, 2013 - ACS Publications
Nuclear magnetic resonance (NMR)-based metabolomics separates exhaled breath
condensate (EBC) profiles of patients affected by pulmonary disease from those of healthy …

Zinc ions coordinated carboxymethyl chitosan-hyaluronic acid microgel for pulmonary drug delivery

Y Yan, Q Wu, P Ren, Q Liu, N Zhang, Y Ji… - International Journal of …, 2021 - Elsevier
Microgel affords a porous and swollen microstructure for the establishment of pulmonary
delivery system with sustained released properties. Here, we report a microgel (with the …

Renal reactivity: acid‐base compensation during incremental ascent to high altitude

SM Zouboules, HC Lafave… - The Journal of …, 2018 - Wiley Online Library
Key points Ascent to high altitude imposes an acid‐base challenge in which renal
compensation is integral for maintaining pH homeostasis, facilitating acclimatization and …

Everything you need to know about distal renal tubular acidosis in autoimmune disease

T Both, R Zietse, EJ Hoorn, PM van Hagen… - Rheumatology …, 2014 - Springer
Renal acid–base homeostasis is a complex process, effectuated by bicarbonate
reabsorption and acid secretion. Impairment of urinary acidification is called renal tubular …

Application of the Rome severity classification of COPD exacerbations in a real-world cohort of hospitalised patients

C Reumkens, A Endres, SO Simons… - ERJ Open …, 2023 - Eur Respiratory Soc
Background Recently, the Rome classification was proposed in which objective and readily
measurable variables were integrated to mark exacerbations of COPD (ECOPD) severity …

Application of system biology to explore the association of neprilysin, angiotensin-converting enzyme 2 (ACE2), and carbonic anhydrase (CA) in pathogenesis of …

R Zolfaghari Emameh, R Falak, E Bahreini - Biological Procedures Online, 2020 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) appears with common symptoms …

[HTML][HTML] Pathophysiology, evaluation, and management of metabolic alkalosis

M Tinawi - Cureus, 2021 - ncbi.nlm.nih.gov
Metabolic alkalosis is an increase in blood pH to> 7.45 due to a primary increase in serum
bicarbonate (HCO 3−). Metabolic alkalosis results from alkali accumulation or acid loss, and …