包含新型环状二核苷酸衍生物的抗体药物偶联物

石崎雅之, 铃木督, 久德真梨子, 雪浦弘志, 原香生子… - 2022 - Google Patents
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …

Sting modulator compounds, and methods of making and using

S Vyskocil, J Ciavarri, C Cullis, DB England… - US Patent …, 2023 - Google Patents
2022-06-15 Assigned to MILLENNIUM PHARMACEUTICALS, INC. reassignment
MILLENNIUM PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …

Antibody-drug conjugates comprising a cyclic dinucleotide

M Yoshikawa, M Saitoh, T Kato… - US Patent App. 18 …, 2024 - Google Patents
US20240066047A1 - Antibody-drug conjugates comprising a cyclic dinucleotide - Google
Patents US20240066047A1 - Antibody-drug conjugates comprising a cyclic dinucleotide …

Sting modulator compounds, and methods of making and using

S Vyskocil, J Ciavarri, C Cullis, DB England… - US Patent …, 2024 - Google Patents
2024-04-05 Assigned to MILLENNIUM PHARMACEUTICALS, INC. reassignment
MILLENNIUM PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE …

Antibody drug conjugates

H Xu, HM Lee, C Arendt - US Patent 11,725,024, 2023 - Google Patents
The present disclosure provides antibody drug conjugates comprising STING modulators.
Also provided are compositions comprising the antibody drug conjugates. The compounds …

Trans-cyclooctene bioorthogonal agents and uses in cancer and immunotherapy

JMM ONETO, S SRINIVASAN, M ZAKHARIAN - 2021 - Google Patents
AOJJSUZBOXZQNB-TZSSRYMLSA-N ADRIAMYCIN Chemical compound O ([C@ H] 1C
[C@@](O)(CC= 2C (O)= C3C (= O) C= 4C= CC= C (C= 4C (= O) C3= C (O) C= 21) OC) C …