The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal
tract of uncertain origin, which includes ulcerative colitis (UC) and Crohn's disease (CD) …

Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC).
The exact cause of IBD remains unknown. Available evidence suggests that an abnormal …

The actions of cannabis are mediated by receptors that are part of an endogenous
cannabinoid system. The endocannabinoid system (ECS) consists of the naturally occurring …

The human gut is a composite anaerobic environment with a large, diverse and dynamic
enteric microbiota, represented by more than 100 trillion microorganisms, including at least …

The peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor
proteins that promote ligand-dependent transcription of target genes that regulate energy …

Background: β-Caryophyllene (BCP) is a natural bicyclic sesquiterpene abundantly found in
essential oils from various spices, fruits and medicinal as well as ornamental plants. It is …

Cannabinoids have shown to have a variety effects on body systems. Through CB1 and CB2
receptors, amongst other, they exert an effect by modulating neurotransmitter and cytokine …