Understanding the diversity of dynamic structures and functions of DNA and RNA in biology
requires tools that can selectively and intimately probe these biomolecules. Synthetic …

Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …

Fluorescent nucleoside analogues (FNAs) are structurally diverse mimics of the natural
essentially non-fluorescent nucleosides which have found numerous applications in probing …

The use of fluorescent nucleic acid base analogues is becoming increasingly important in
the fields of biology, biochemistry and biophysical chemistry as well as in the field of DNA …

A fluorescent ribonucleoside alphabet consisting of highly emissive purine (th A, th G) and
pyrimidine (th U, th C) analogues, all derived from thieno [3, 4-d] pyrimidine as the …

Molecular beacons (MBs) have been used as viable fluorescent probes in nucleic acid
analysis. Many researchers around the world continue to modify the MBs to suit their needs …

FLT3 kinase is a potential drug target in acute myeloid leukemia (AML). Patients with FLT3
mutations typically have higher relapse rates and worse outcomes than patients without …

Conspectus In 1960, Weber prophesied that “There are many ways in which the properties
of the excited state can be utilized to study points of ignorance of the structure and function …

The response of DNA and RNA bases to ultraviolet (UV) radiation has been receiving
increasing attention for a number of important reasons:(i) the selection of the building blocks …

Recent years has witnessed increasing development and exploitation of fluorescence
techniques which has been spurred by the discovery, design and synthesis of novel …