[HTML][HTML] Circular RNAs: Characterization, cellular roles, and applications

CX Liu, LL Chen - Cell, 2022 - cell.com
Most circular RNAs are produced from the back-splicing of exons of precursor mRNAs.
Recent technological advances have in part overcome problems with their circular …

Integrated lncRNA function upon genomic and epigenomic regulation

AB Herman, D Tsitsipatis, M Gorospe - Molecular Cell, 2022 - cell.com
Although some long noncoding (lnc) RNAs are known since the 1950s, the past 25 years
have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The …

Best practice standards for circular RNA research

AF Nielsen, A Bindereif, I Bozzoni, M Hanan… - Nature …, 2022 - nature.com
Circular RNAs (circRNAs) are formed in all domains of life and via different mechanisms.
There has been an explosion in the number of circRNA papers in recent years; however, as …

Circular RNAs as emerging players in cervical cancer tumorigenesis; a review to roles and biomarker potentials

S Najafi - International Journal of Biological Macromolecules, 2022 - Elsevier
Cervical cancer is the most lethal gynecological cancer among women worldwide. Most of
the patients are diagnosed at the advanced stages due to late diagnosis and lack of …

Crosstalk between N6-methyladenosine modification and circular RNAs: current understanding and future directions

X Wang, R Ma, X Zhang, L Cui, Y Ding, W Shi, C Guo… - Molecular cancer, 2021 - Springer
Abstract N 6-methyladenosine (m 6 A) is a prevalent internal modification in eukaryotic
RNAs regulated by the so-called “writers”,“erasers”, and “readers”. m 6 A has been …

Biogenesis, functions, and clinical implications of circular RNAs in non-small cell lung cancer

Y Liu, X Ao, W Yu, Y Zhang, J Wang - Molecular Therapy-Nucleic Acids, 2022 - cell.com
Lung cancer (LC) is the leading cause of cancer-related deaths worldwide, with high
morbidity and mortality. Non-small cell lung cancer (NSCLC) is a major pathological type of …

Emerging role of circular RNA–protein interactions

A Das, T Sinha, S Shyamal, AC Panda - Non-coding RNA, 2021 - mdpi.com
Circular RNAs (circRNAs) are emerging as novel regulators of gene expression in various
biological processes. CircRNAs regulate gene expression by interacting with cellular …

Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production

X Yao, H Liu, Z Wang, F Lu, W Chen, Q Feng, Y Miao… - Oncogene, 2023 - nature.com
Circular RNAs (circRNAs) play an important role in regulating the development of human
cancers through diverse biological functions. However, the exact molecular mechanisms …

New molecular mechanisms and clinical impact of circRNAs in human cancer

G Fontemaggi, C Turco, G Esposito, S Di Agostino - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) belong to a new class of non-coding RNAs
implicated in cellular physiological functions but also in the evolution of various human …

Targeting lncRNA DDIT4‐AS1 sensitizes triple negative breast cancer to chemotherapy via suppressing of autophagy

T Jiang, J Zhu, S Jiang, Z Chen, P Xu… - Advanced …, 2023 - Wiley Online Library
In this study, it is found that the lncRNA, DNA damage inducible transcript 4 antisense RNA1
(DDIT4‐AS1), is highly expressed in triple‐negative breast cancer (TNBC) cell lines and …