Genome-wide association study of brain connectivity changes for Alzheimer's disease

SSM Elsheikh, ER Chimusa, NJ Mulder, A Crimi - Scientific reports, 2020 - nature.com
Variations in the human genome have been found to be an essential factor that affects
susceptibility to Alzheimer's disease. Genome-wide association studies (GWAS) have …

Decreased dynamism of overlapping brain sub-networks in major depressive disorder

N Chen, J Shi, Y Li, S Ji, Y Zou, L Yang, Z Yao… - Journal of psychiatric …, 2021 - Elsevier
Abstract Major Depressive Disorder (MDD) is increasingly recognized as a common brain
disorder with aberrant brain networks. Alterations in dynamic functional brain networks have …

Age-related changes in human brain functional connectivity using graph theory and machine learning techniques in resting-state fMRI data

S Baghernezhad, MR Daliri - GeroScience, 2024 - Springer
Aging is the basis of neurodegeneration and dementia that affects each endemic in the
body. Normal aging in the brain is associated with progressive slowdown and disruptions in …

Multi-stage association analysis of glioblastoma gene expressions with texture and spatial patterns

SSM Elsheikh, S Bakas, NJ Mulder… - … Sclerosis, Stroke and …, 2019 - Springer
Glioblastoma is the most aggressive malignant primary brain tumor with a poor prognosis.
Glioblastoma heterogeneous neuroimaging, pathologic, and molecular features provide …

Relating global and local connectome changes to dementia and targeted gene expression in Alzheimer's disease

SSM Elsheikh, ER Chimusa… - Frontiers in human …, 2021 - frontiersin.org
Networks are present in many aspects of our lives, and networks in neuroscience have
recently gained much attention leading to novel representations of brain connectivity. The …

Bigen: integrative clinical and brain-imaging genetics analysis using structural equation model

SSM Elsheikh, ER Chimusa, A Crimi, NJ Mulder - bioRxiv, 2020 - biorxiv.org
The identification of genetic variants associated with complex brain diseases has evolved in
the past decades. Studies in the field have taken different approaches and study designs …

Integration of multi-omic data and neuroimaging characteristics in studying brain related diseases

SSM Elsheikh - 2020 - open.uct.ac.za
Approaches to the identification of genetic variants associated with complex brain diseases
have evolved in recent decades. This evolution was supported by advancements in medical …