As a therapeutic group, non-steroidal anti-inflammatory drugs (NSAIDs) are among the most
widely used, prescribed and over the counter (OTC) medications for the treatment of …

Brain specific drug delivery is one of the most interesting and challenging areas of research.
The blood-brain barrier separates the brain from blood and acts as a barrier to protect the …

Inflammation mediators, prostaglandins are causing inflammation, pain and pyrexia in the
body. Synthesis of these mediators can be effectively blocked by administering the non …

Neuroinflammation may be a pathogenic mediator and biomarker of neurodegeneration at
the boundary between mild cognitive impairment (MCI) and early-stage Alzheimer's disease …

A series of anti-inflammatory derivatives containing an N-acyl hydrazone subunit (4a–e)
were synthesized and characterized. Docking studies were performed that suggest that …

Oral delivery of poorly bioavailable therapeuticals is challenging. The challenges are more
serious when physiological factors of gut such as cytochrome P450, P-glycoprotein …

We report the first example of B (C6F5) 3-catalyzed O–H insertion reaction of sulfoxonium
ylides and carboxylic acids, achieving efficient construction of diester moieties under metal …

Aim: Cancer patients undergoing chemotherapy report cognitive changes collectively
termed “chemo brain.” Neuroinflammation is among the factors believed to contribute to …

A copper (II)-catalyzed 1, 8-diazabicyclo [5.4. 0] undec-7-ene (DBU)-mediated synthesis of α-
acyloxyacetates from α-azidoketones and diazoacetates under visible light at room …

The use of surfactants in drug delivery has offered several advantages. Quantitative
knowledge of the interactions of drugs with micellar systems is essential for deriving …