Modeling human cardiac arrhythmias: insights from zebrafish

S Gauvrit, J Bossaer, J Lee, MM Collins - Journal of Cardiovascular …, 2022 - mdpi.com
Cardiac arrhythmia, or irregular heart rhythm, is associated with morbidity and mortality and
is described as one of the most important future public health challenges. Therefore …

Human heart morphogenesis: a new vision based on in vivo labeling and cell tracking

L Villavicencio-Guzmán, C Sánchez-Gómez… - Life, 2023 - mdpi.com
Despite the extensive information available on the different genetic, epigenetic, and
molecular features of cardiogenesis, the origin of congenital heart defects remains unknown …

Control of cardiac contractions using Cre-lox and degron strategies in zebrafish

T Juan, M Bellec, B Cardoso, H Athéa… - Proceedings of the …, 2024 - National Acad Sciences
Cardiac contractions and hemodynamic forces are essential for organ development and
homeostasis. Control over cardiac contractions can be achieved pharmacologically or …

Environmental exposure to triazole fungicide causes left-right asymmetry defects and contributes to abnormal heart development in zebrafish embryos by activating …

Y Wang, Y Ren, X Ning, G Li, N Sang - Science of The Total Environment, 2023 - Elsevier
Triazole fungicides have been widely used all over the world. However, their potential
ecological safety and health risks remain unclear, especially their cardiac developmental …

Effect of hyperglycemia on tbx5a and nppa gene expression and its correlation to structural and functional changes in developing zebrafish heart

S Sankar, M Jayabalan, S Venkatesh… - Cell Biology …, 2022 - Wiley Online Library
The objective of the current study is to analyze the effects of gestational diabetes on
structural and functional changes in correlation with these two essential regulators of …

The Mechanics of Building Functional Organs

TGR Andrews, R Priya - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Organ morphogenesis is multifaceted, multiscale, and fundamentally a robust process.
Despite the complex and dynamic nature of embryonic development, organs are built with …

Norflurazon causes developmental defects including cardiovascular abnormalities in earlystage zebrafish (Danio rerio)

G An, H Park, T Hong, G Song… - 한국동물생명공학회지(구 …, 2022 - db.koreascholar.com
Norflurazon is widely used on agricultural lands and has a high potential to pollute water
sources. However, its effects on fish have not been fully elucidated. The purpose of our study …

Zebrafish smarcc1a mutants reveal requirements for BAF chromatin remodeling complexes in distinguishing the atrioventricular canal from the cardiac chambers

HJ Auman, IH Fernandes… - Developmental …, 2024 - Wiley Online Library
Background Essential patterning processes transform the heart tube into a
compartmentalized organ with distinct chambers separated by an atrioventricular canal …

Early heart development: examining the dynamics of function-form emergence

N Combémorel, N Cavell… - Biochemical Society …, 2024 - portlandpress.com
During early embryonic development, the heart undergoes a remarkable and complex
transformation, acquiring its iconic four-chamber structure whilst concomitantly contracting to …

Cardiac Development and Factors Influencing the Development of Congenital Heart Defects (CHDs): Part I

M Zubrzycki, R Schramm, A Costard-Jäckle… - International Journal of …, 2024 - mdpi.com
The traditional description of cardiac development involves progression from a cardiac
crescent to a linear heart tube, which in the phase of transformation into a mature heart …