Over the past few years, MRI has become an indispensable tool for diagnosing multiple
sclerosis (MS). However, the current MRI criteria for MS diagnosis have imperfect sensitivity …

The clinical use of MRI in patients with multiple sclerosis (MS) has advanced markedly over
the past few years. Technical improvements and continuously emerging data from clinical …

Cognitive impairment (CI) is common and debilitating in patients with multiple sclerosis.
However, little is known about how different disease courses affect CI, impeding prognosis …

Background: The central vein sign (CVS) is a radiological feature proposed as a multiple
sclerosis (MS) imaging biomarker able to accurately differentiate MS from other white matter …

Introduction In patients with multiple sclerosis (MS), conventional magnetic resonance
imaging (MRI) provides only limited insights into the nature of brain damage with modest …

Background Alzheimer disease (AD) affects at least 5 million individuals in the USA alone
stimulating an intense search for disease prevention and treatment therapies as well as for …

Objective The diagnosis of multiple sclerosis (MS) presently relies on radiographic
assessments of imperfect specificity. Recent data using T2* methodology for the detection of …

Purpose Physiological fluctuations in biological tissues adversely affect MR images if
present during signal acquisition. This problem is especially important for quantitative MRI …

We aimed to evaluate the pooled incidence of central vein sign on T2*-weighted images
from patients with multiple sclerosis (MS), and to determine the diagnostic performance of …

Quantitative susceptibility mapping is a potentially powerful technique for mapping tissue
magnetic susceptibility from gradient recalled echo (GRE) MRI signal phase. In this review …