Brain homeostasis: VEGF receptor 1 and 2—two unequal brothers in mind

IM Wittko-Schneider, FT Schneider, KH Plate - Cellular and Molecular Life …, 2013 - Springer
Vascular endothelial growth factors (VEGFs), initially thought to act specifically on the
vascular system, exert trophic effects on neural cells during development and adulthood …

Current disease modifying approaches to treat Parkinson's disease

D Lindholm, J Mäkelä, V Di Liberto, G Mudo… - Cellular and Molecular …, 2016 - Springer
Parkinson's disease (PD is a progressive neurological disorder characterized by the
degeneration and death of midbrain dopamine and non-dopamine neurons in the brain …

Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering …

K Matsubara, Y Matsushita, K Sakai… - Journal of …, 2015 - Soc Neuroscience
Engrafted mesenchymal stem cells from human deciduous dental pulp (SHEDs) support
recovery from neural insults via paracrine mechanisms that are poorly understood. Here we …

[HTML][HTML] Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson's disease

MH Voutilainen, U Arumäe, M Airavaara, M Saarma - FEBS letters, 2015 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disorder where dopamine
(DA) neurons in the substantia nigra degenerate and die. Since no cure for PD exists, there …

The role of fibromodulin in cancer pathogenesis: implications for diagnosis and therapy

MH Pourhanifeh, R Mohammadi, S Noruzi… - Cancer cell …, 2019 - Springer
Fibromodulin (FMOD) is known as one of very important extracellular matrix small leucine-
rich proteoglycans. This small leucine-rich proteoglycan has critical roles in the extracellular …

Neurotrophic factors hold promise for the future of Parkinson's disease treatment: is there a light at the end of the tunnel?

A Nasrolahi, J Mahmoudi, A Akbarzadeh… - Reviews in the …, 2018 - degruyter.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder and is
characterized by a spectrum of clinicopathologic signs and a complex etiology. PD results …

ELK3 expressed in lymphatic endothelial cells promotes breast cancer progression and metastasis through exosomal miRNAs

KS Kim, JI Park, N Oh, HJ Cho, JH Park, KS Park - Scientific reports, 2019 - nature.com
Tumor-associated lymphatic vessels (LV) serve as a route of cancer dissemination through
the prometastatic crosstalk between lymphatic endothelial cells (LECs) lining the LVs and …

BDNF pretreatment of human embryonic-derived neural stem cells improves cell survival and functional recovery after transplantation in hypoxic–ischemic stroke

S Rosenblum, TN Smith, N Wang, JY Chua… - Cell …, 2015 - journals.sagepub.com
Intra-arterial neural stem cell (NSC) therapy has the potential to improve long-term outcomes
after stroke. Here we evaluate if pretreatment of NSCs with brain-derived neurotrophic factor …

Anti-VEGF treatment of corneal neovascularization

AM Keating, DS Jacobs - The ocular surface, 2011 - Elsevier
Vascular endothelial growth factor (VEGF) is an angiogenic factor shown to be a critical
secreted cytokine in tumorigenesis and retinal neovascularization (NV). Currently, there are …

Gene and protein therapies utilizing VEGF for ALS

OP Keifer Jr, DM O'Connor, NM Boulis - Pharmacology & Therapeutics, 2014 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that is
usually fatal within 2–5 years. Unfortunately, the only treatment currently available is riluzole …