In the past decade, the term organoid has moved from obscurity to common use to describe
a 3D in vitro cellular model of a tissue that recapitulates structural and functional elements of …

Deconstructing and then reconstructing developmental processes ex vivo is crucial to
understanding how organs assemble and how physiology can be disrupted in disease …

Biological computing (or biocomputing) offers potential advantages over silicon-based
computing in terms of faster decision-making, continuous learning during tasks, and greater …

The assembly of cortical circuits involves the generation and migration of interneurons from
the ventral to the dorsal forebrain,–, which has been challenging to study at inaccessible …

The biofabrication of three-dimensional (3D) tissues that recapitulate organ-specific
architecture and function would benefit from temporal and spatial control of cell-cell …

Abstract Lewy bodies (LBs), α-synuclein-enriched intracellular inclusions, are a hallmark of
Parkinson's disease (PD) pathology, yet a cellular model for LB formation remains elusive …

Human brain organoids provide unique platforms for modeling several aspects of human
brain development and pathology. However, current brain organoid systems mostly lack the …

Importance Climate change, pollution, urbanization, socioeconomic inequality, and
psychosocial effects of the COVID-19 pandemic have caused massive changes in …

We are entering an era of medicine where increasingly sophisticated data will be obtained
from patients to determine proper diagnosis, predict outcomes and direct therapies. We …

Psychiatric disorders are often distinguished from neurological disorders in that the former
do not have characteristic lesions or findings from cerebrospinal fluid …