Mitochondrial fatty acid oxidation is an essential pathway for energy production, especially
during prolonged fasting and sub-maximal exercise. Long-chain fatty acids are the most …

Perturbations in metabolic pathways can cause substantial increases in plasma and tissue
concentrations of long-chain acylcarnitines (LCACs). For example, the levels of LCACs and …

Current healthcare practices are reactive and use limited physiological and clinical
information, often collected months or years apart. Moreover, the discovery and profiling of …

Consultation for liver disease in pregnant women is a common and oftentimes vexing
clinical consultation for the gastroenterologist. The challenge lies in the need to consider the …

Fatty acid oxidation disorders (FAODs) are inborn errors of metabolism due to disruption of
either mitochondrial β-oxidation or the fatty acid transport using the carnitine transport …

Mitochondrial fatty acid oxidation (FAO) plays a pivotal role in maintaining body energy
homoeostasis mainly during catabolic states. Oxidation of fatty acids requires approximately …

Clinical exome sequencing (CES) has become an increasingly popular diagnostic tool in
patients with heterogeneous genetic disorders, especially in those with neurocognitive …

Exposure to micro‐and nanoplastics (MNPs) is common because of their omnipresence in
environment. Recent studies have revealed that MNPs may cause atherosclerosis, but the …

Fatty acid oxidation disorders (FAOD) are a group of rare, autosomal recessive, metabolic
disorders caused by variants of the genes for the enzymes and proteins involved in the …

Mitochondrial fatty acid oxidation disorders (FAODs) are caused by defects in β-oxidation
enzymes, including very long-chain acyl-CoA dehydrogenase (VLCAD), trifunctional protein …