Isoxazole derivatives as regulators of immune functions
M Zimecki, U Bąchor, M Mączyński - Molecules, 2018 - mdpi.com
In this review, we present reports on the immunoregulatory properties of isoxazole
derivatives classified into several categories, such as immunosuppressive, anti …
derivatives classified into several categories, such as immunosuppressive, anti …
[HTML][HTML] Coumarin-heterocycle framework: A privileged approach in promising anticancer drug design
A Dorababu - European Journal of Medicinal Chemistry Reports, 2021 - Elsevier
The cancer cases are increasing in fast pace; most of them are resulted from exposure to
harmful pollutants. Genetic factors are responsible for cancer only to a small extent …
harmful pollutants. Genetic factors are responsible for cancer only to a small extent …
Production of active pharmaceutical ingredients (APIs) from lignin-derived phenol and catechol
Active pharmaceutical ingredients (APIs) constitute a significant and growing global market.
In the past few decades, labor costs, concerns regarding chemical waste, and more stringent …
In the past few decades, labor costs, concerns regarding chemical waste, and more stringent …
Synthesis of new coumarin tethered isoxazolines as potential anticancer agents
A series of new coumarin tethered isoxazolines (7a-l) were synthesized and evaluated for
their cytotoxic potency against human melanoma cancer cell line (UACC 903) as well as …
their cytotoxic potency against human melanoma cancer cell line (UACC 903) as well as …
Synthesis of aspirin-curcumin mimic conjugates of potential antitumor and anti-SARS-CoV-2 properties
Abstract Series of piperidone-salicylate conjugates were synthesized through the reaction of
3E, 5E-bis (arylidene)-4-piperidones with the appropriate acid chloride of acetylsalicylate in …
3E, 5E-bis (arylidene)-4-piperidones with the appropriate acid chloride of acetylsalicylate in …
Isoxazole Derivatives against Carbonic Anhydrase: Synthesis, Molecular Docking, MD Simulations, and Free Energy Calculations Coupled with In Vitro Studies
Heterocyclic compounds with a five-membered ring as a core, particularly those containing
more than one heteroatom, have a wide spectrum of biological functions, especially in …
more than one heteroatom, have a wide spectrum of biological functions, especially in …
Gold redox catalysis for cyclization/arylation of allylic oximes: synthesis of isoxazoline derivatives
Base-assisted diazonium activation has been employed to promote gold (I)/(III) redox
catalysis toward allylic oxime cyclization/aryl coupling. Functional isoxazolines were …
catalysis toward allylic oxime cyclization/aryl coupling. Functional isoxazolines were …
Salicylic acid: synthetic strategies and their biological activities
Phenolic acids are the phytochemicals formthe key part of the organic chemistry and are
widely found in the plants, plant foods and human metabolites possessing a wide range of …
widely found in the plants, plant foods and human metabolites possessing a wide range of …
[2+ 2+ 1] Cycloaddition of N-tosylhydrazones, tert-butyl nitrite and alkenes: a general and practical access to isoxazolines
L Ma, F Jin, X Cheng, S Tao, G Jiang, X Li, J Yang… - Chemical …, 2021 - pubs.rsc.org
N-Tosylhydrazones have proven to be versatile synthons over the past several decades.
However, to our knowledge, the construction of isoxazolines based on N-tosylhydrazones …
However, to our knowledge, the construction of isoxazolines based on N-tosylhydrazones …
Green synthesis of 3-substituted-4-arylmethylideneisoxazol-5 (4H)-one derivatives catalyzed by salicylic acid
A Mosallanezhad, H Kiyani - Current Organocatalysis, 2019 - ingentaconnect.com
Background: 4-Arylmethylideneisoxazol-5 (4H)-ones are a class of organic compounds with
a variety of applications in the agriculture, filter dyes, photonic devices, and pharmaceutical …
a variety of applications in the agriculture, filter dyes, photonic devices, and pharmaceutical …