Generic acquisition protocol for quantitative MRI of the spinal cord

J Cohen-Adad, E Alonso-Ortiz, M Abramovic… - Nature protocols, 2021 - nature.com
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Traumatic and nontraumatic spinal cord injury: pathological insights from neuroimaging

G David, S Mohammadi, AR Martin… - Nature Reviews …, 2019 - nature.com
Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …

Research progress of antioxidants in oxidative stress therapy after spinal cord injury

C Zhang, T Zhai, J Zhu, D Wei, S Ren, Y Yang… - Neurochemical …, 2023 - Springer
Spinal cord injury (SCI) is a serious problem in the central nervous system resulting in high
disability and mortality with complex pathophysiological mechanisms. Oxidative stress is …

Conductive collagen-based hydrogel combined with electrical stimulation to promote neural stem cell proliferation and differentiation

X Xu, L Wang, J Jing, J Zhan, C Xu, W Xie… - … in Bioengineering and …, 2022 - frontiersin.org
Injectable biomimetic hydrogels are a promising strategy for enhancing tissue repair after
spinal cord injury (SCI) by restoring electrical signals and increasing stem cell differentiation …

Investigation of perfusion impairment in degenerative cervical myelopathy beyond the site of cord compression

A Lebret, S Lévy, N Pfender, M Farshad, FCS Altorfer… - Scientific Reports, 2023 - nature.com
The aim of this study was to determine tissue-specific blood perfusion impairment of the
cervical cord above the compression site in patients with degenerative cervical myelopathy …

Nrf2 signaling in the oxidative stress response after spinal cord injury

X Guo, J Kang, Z Wang, Y Wang, M Liu, D Zhu, F Yang… - Neuroscience, 2022 - Elsevier
Spinal cord injury (SCI) is a central nervous system trauma that can cause severe
neurological impairment. A series of pathological and physiological changes after SCI (eg …

[HTML][HTML] Reliability of multi-parameter mapping (MPM) in the cervical cord: A multi-center multi-vendor quantitative MRI study

M Seif, T Leutritz, S Schading, T Emmengger, A Curt… - Neuroimage, 2022 - Elsevier
MRI based multicenter studies which target neurological pathologies affecting the spinal
cord and brain–including spinal cord injury (SCI)–require standardized acquisition protocols …

Tracking white and gray matter degeneration along the spinal cord axis in degenerative cervical myelopathy

K Vallotton, G David, M Hupp, N Pfender… - Journal of …, 2021 - liebertpub.com
This study aims to determine tissue-specific neurodegeneration across the spinal cord in
patients with mild-moderate degenerative cervical myelopathy (DCM). Twenty-four mild …

Extent of cord pathology in the lumbosacral enlargement in non-traumatic versus traumatic spinal cord injury

G David, K Vallotton, M Hupp, A Curt… - Journal of …, 2022 - liebertpub.com
This study compares remote neurodegenerative changes caudal to a cervical injury in
degenerative cervical myelopathy (DCM; ie, non-traumatic) and incomplete traumatic spinal …

Proposing a framework to understand the role of imaging in degenerative cervical myelopathy: enhancement of MRI protocols needed for accurate diagnosis and …

CM Zipser, MG Fehlings, K Margetis, A Curt, M Betz… - Spine, 2022 - journals.lww.com
DCM is an important, disabling and unfortunately frequently overlooked condition, which is
estimated to affect as many as one in 50 adults. 1–4 Despite the prevalence of DCM …