The role of Toll-like receptors and neuroinflammation in Parkinson's disease

A Heidari, N Yazdanpanah, N Rezaei - Journal of Neuroinflammation, 2022 - Springer
Background Parkinson's disease (PD) is the second most prevalent neurodegenerative
disorder, characterized by motor and non-motor symptoms, significantly affecting patients' …

Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis

D Kashyap, VK Garg, N Goel - Advances in protein chemistry and structural …, 2021 - Elsevier
Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological …

Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Medicinal Fungus Cordyceps with Its Nutraceutical and Therapeutic …

SA Ashraf, AEO Elkhalifa, AJ Siddiqui, M Patel… - Molecules, 2020 - mdpi.com
Cordyceps is a rare naturally occurring entomopathogenic fungus usually found at high
altitudes on the Himalayan plateau and a well-known medicinal mushroom in traditional …

[HTML][HTML] Cordyceps spp.: A review on its immune-stimulatory and other biological potentials

G Das, HS Shin, G Leyva-Gómez… - Frontiers in …, 2021 - frontiersin.org
In recent decades, interest in the Cordyceps genus has amplified due to its
immunostimulatory potential. Cordyceps species, its extracts, and bioactive constituents …

Nutritional composition, health benefits, and application value of edible insects: a review

Y Zhou, D Wang, S Zhou, H Duan, J Guo, W Yan - Foods, 2022 - mdpi.com
For thousands of years, edible insects have been used as food to alleviate hunger and
improve malnutrition. Some insects have also been used as medicines because of their …

Neuroinflammation and blood–brain barrier disruption following traumatic brain injury: pathophysiology and potential therapeutic targets

S Sulhan, KA Lyon, LA Shapiro… - Journal of neuroscience …, 2020 - Wiley Online Library
Abstract Traumatic Brain Injury (TBI) is the most frequent cause of death and disability in
young adults and children in the developed world, occurring in over 1.7 million persons and …

Ursolic acid (UA): A metabolite with promising therapeutic potential

D Kashyap, HS Tuli, AK Sharma - Life sciences, 2016 - Elsevier
Plants are known to produce a variety of bioactive metabolites which are being used to cure
various life threatening and chronic diseases. The molecular mechanism of action of such …

[PDF][PDF] Fungal cordycepin biosynthesis is coupled with the production of the safeguard molecule pentostatin

Y Xia, F Luo, Y Shang, P Chen, Y Lu, C Wang - Cell chemical biology, 2017 - cell.com
Cordycepin (COR) and pentostatin (PTN) are adenosine analogs with related bioactivity
profiles as both mimic adenosine and can inhibit some of the processes that are adenosine …

Kaempferol–A dietary anticancer molecule with multiple mechanisms of action: Recent trends and advancements

D Kashyap, A Sharma, HS Tuli, K Sak, S Punia… - Journal of functional …, 2017 - Elsevier
The consumption of diet-based naturally bioactive metabolites is preferred to synthetic
material in order to avert health-associated disorders. Among the plant-derived polyphenols …

[PDF][PDF] Cordycepin ameliorates nonalcoholic steatohepatitis by activation of the AMP‐activated protein kinase signaling pathway

T Lan, Y Yu, J Zhang, H Li, Q Weng, S Jiang… - …, 2021 - Wiley Online Library
Background and Aims Nonalcoholic fatty liver disease, especially nonalcoholic
steatohepatitis (NASH), has become a major cause of liver transplantation and liver …