Cisplatin is widely used for the treatment of a number of solid malignant tumors. However,
ototoxicity induced by cisplatin is an obstacle to effective treatment of tumors. The basis for …

Dithiocarbamates (DTCs) have been used for various applications, including as hardening
agents in rubber manufacturing, as fungicide in agriculture, and as medications to treat …

In this article, we describe a method of delivery of doxorubicin using a novel tumor-homing
peptide-based albumin nanoparticle system to triple-negative breast cancer cells (TNBC) …

Four iridium/ruthenium half-sandwich metal complexes containing 8-hydroxyquinoline
ligands were synthesized as anticancer agents. In vitro toxicity results showed that all …

Cadmium (Cd) is a toxic heavy metal, exposure to which leads to adverse health effects
including chronic kidney damage. Tremendous efforts have been explored in identifying …

Many cancer patients suffer permanent hearing loss due to accumulation of ototoxic cisplatin
in the inner ear. In this study, two types of 100 nm magnetic micelles were developed to …

Premature ovarian insufficiency (POI) is one of the important causes of female infertility. Yet
the aetiology for POI is still elusive. FBXW7 (F‐box with 7 tandem WD) is one of the …

This review presents an overview of the antitumor properties of various platinum (II)
complexes of dithiocarbamates. It has been noticed that in several cases the activity is …

This work describes the synthesis and total characterization of five novel Pt II complexes of
the type trans-[Pt (L) 2 (PPh 3) 2](L= 5-alkyl-1, 3, 4-oxadiazol-2-thione derivatives and PPh …

Cisplatin is one of the most effective chemotherapeutic agents used for the treatment of a
wide variety of cancers. However, cisplatin has been associated with nephrotoxicity, which …