Updates on RPE cell damage in diabetic retinopathy

M Li, M Tian, Y Wang, H Ma… - Molecular …, 2023 - spandidos-publications.com
Diabetic retinopathy (DR) is a microvascular complication of diabetes. The retinal pigment
epithelium (RPE) forms the outer layer of the blood-retinal barrier and serves a role in …

Historical, current and future approaches to surgery for rhegmatogenous retinal detachment

H Kunikata, T Abe, T Nakazawa - The Tohoku journal of …, 2019 - jstage.jst.go.jp
Rhegmatogenous retinal detachment (RRD) is a serious condition that can cause blindness
without surgical treatment. RRD occurs when a retinal tear or hole allows fluid to accumulate …

Molecular pathogenesis of rhegmatogenous retinal detachment

T Öhman, L Gawriyski, S Miettinen, M Varjosalo… - Scientific reports, 2021 - nature.com
Rhegmatogenous retinal detachment (RRD) is an ophthalmic emergency, which usually
requires prompt surgery to prevent further detachment and restore sensory function …

[HTML][HTML] MicroRNAs in the vitreous humor of patients with retinal detachment and a different grading of proliferative vitreoretinopathy: a pilot study

MD Toro, M Reibaldi, T Avitabile… - … Vision Science & …, 2020 - iovs.arvojournals.org
Purpose: Although the expression of microRNAs (miRNAs) in retinal pigment epithelial
(RPE) cells undergoing epithelial-mesenchymal transition (EMT) is involved in the …

New therapeutic perspectives in the treatment of uveal melanoma: A systematic review

MD Toro, L Gozzo, L Tracia, M Cicciù, F Drago… - Biomedicines, 2021 - mdpi.com
Uveal melanoma (UM) is a rare disease, but the most common primary intraocular cancer,
mostly localized in the choroid. Currently, the first-line treatment options for UM are radiation …

Biomarkers for PVR in rhegmatogenous retinal detachment

S Zandi, IB Pfister, PG Traine, C Tappeiner, A Despont… - PloS one, 2019 - journals.plos.org
Purpose Various profibrotic and proinflammatory cytokines have been found upregulated in
uncomplicated primary retinal detachment (pRD), but without providing a uniform picture …

[HTML][HTML] Intravitreal methotrexate

F Abdi, SS Mohammadi… - Journal of Ophthalmic & …, 2021 - ncbi.nlm.nih.gov
Intravitreal methotrexate (MTX) has been proven to be an effective treatment for various
intraocular diseases. In this article, a comprehensive review was performed on intravitreal …

Evolving treatment paradigm in the management of diabetic macular edema in the era of COVID-19

C Iovino, E Peiretti, G Giannaccare, V Scorcia… - Frontiers in …, 2021 - frontiersin.org
Intravitreal therapy is widely recognized as a major milestone in ophthalmology being one of
the most commonly performed ocular procedures (He et al., 2018). The spread of …

Statin use and vitreoretinal surgery: Findings from a Finnish population‐based cohort study

S Loukovaara, S Sahanne, A Takala… - Acta …, 2018 - Wiley Online Library
Purpose Vitreoretinal (VR) surgery is the third most common intraocular surgery after
refractive and cataract surgery. The impact of statin therapy on VR surgery outcomes …

Preoperative, intraoperative and postoperative corticosteroid use as an adjunctive treatment for rhegmatogenous retinal detachment

V Bonfiglio, M Reibaldi, I Macchi, M Fallico… - Journal of Clinical …, 2020 - mdpi.com
The treatment for rhegmatogenous retinal detachment (RRD) is surgery, including pars
plana vitrectomy (PPV) and scleral buckling (SB). Despite surgical advances, degeneration …