Soft bioelectronics based on nanomaterials

KW Cho, SH Sunwoo, YJ Hong, JH Koo… - Chemical …, 2021 - ACS Publications
Recent advances in nanostructured materials and unconventional device designs have
transformed the bioelectronics from a rigid and bulky form into a soft and ultrathin form and …

3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate

J Nicolas, S Magli, L Rabbachin, S Sampaolesi… - …, 2020 - ACS Publications
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Multivascular networks and functional intravascular topologies within biocompatible hydrogels

B Grigoryan, SJ Paulsen, DC Corbett, DW Sazer… - Science, 2019 - science.org
Solid organs transport fluids through distinct vascular networks that are biophysically and
biochemically entangled, creating complex three-dimensional (3D) transport regimes that …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Advances in extrusion 3D bioprinting: a focus on multicomponent hydrogel‐based bioinks

X Cui, J Li, Y Hartanto, M Durham… - Advanced …, 2020 - Wiley Online Library
Abstract 3D bioprinting involves the combination of 3D printing technologies with cells,
growth factors and biomaterials, and has been considered as one of the most advanced …

Deconstructing the third dimension–how 3D culture microenvironments alter cellular cues

BM Baker, CS Chen - Journal of cell science, 2012 - journals.biologists.com
Much of our understanding of the biological mechanisms that underlie cellular functions,
such as migration, differentiation and force-sensing has been garnered from studying cells …

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

S Khetan, M Guvendiren, WR Legant, DM Cohen… - Nature materials, 2013 - nature.com
Although cell–matrix adhesive interactions are known to regulate stem cell differentiation,
the underlying mechanisms, in particular for direct three-dimensional encapsulation within …

Design properties of hydrogel tissue-engineering scaffolds

J Zhu, RE Marchant - Expert review of medical devices, 2011 - Taylor & Francis
This article summarizes the recent progress in the design and synthesis of hydrogels as
tissue-engineering scaffolds. Hydrogels are attractive scaffolding materials owing to their …

Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates

IS Kinstlinger, SH Saxton, GA Calderon… - Nature biomedical …, 2020 - nature.com
Sacrificial templates for patterning perfusable vascular networks in engineered tissues have
been constrained in architectural complexity, owing to the limitations of extrusion-based 3D …

Matrix degradability controls multicellularity of 3D cell migration

B Trappmann, BM Baker, WJ Polacheck… - Nature …, 2017 - nature.com
A major challenge in tissue engineering is the development of materials that can support
angiogenesis, wherein endothelial cells from existing vasculature invade the surrounding …