Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial
ischemia with or without reperfusion, and basic and translational research is needed to …

The increase in the life expectancy of patients with renal cell carcinoma (RCC) in the last
decade is due to changes that have occurred in the area of preclinical studies …

Many cancer treatments, such as those for managing recalcitrant tumors like pancreatic
ductal adenocarcinoma, cause off-target toxicities in normal, healthy tissue, highlighting the …

First described in 2003, the dissolution dynamic nuclear polarization (DNP) technique,
combined with 13 C magnetic resonance spectroscopy (MRS), has since been used in …

Here, we provide an in-depth analysis of the usefulness of single-sample metabolite/RNA
extraction for multi-'omics readout. Using pulverized frozen livers of mice injected with …

Cellular redox is intricately linked to energy production and normal cell function. Although
the redox states of mitochondria and cytosol are connected by shuttle mechanisms, the …

Background The heart relies on continuous energy production and imbalances herein
impair cardiac function directly. The tricarboxylic acid (TCA) cycle is the primary means of …

We report on the assembly and performance evaluation of a 180‐GHz/6.4 T dynamic
nuclear polarization (DNP) system based on a cryogen‐free superconducting magnet. The …

Mitochondrial dysfunction is considered to be an important component of many metabolic
diseases yet there is no reliable imaging biomarker for monitoring mitochondrial damage in …

Cardiovascular disease is the leading cause of death world-wide. It is increasingly
recognised that cardiac pathologies show, or may even be caused by, changes in …