Molecular and regulatory mechanisms of oxidative stress adaptation in Streptococcus mutans

S Yu, Q Ma, Y Li, J Zou - Molecular Oral Microbiology, 2023 - Wiley Online Library
Dental caries is a chronic progressive disease, which destructs dental hard tissues under
the influence of multiple factors, mainly bacteria. Streptococcus mutans is the main …

Comparative Genome Analysis of Megasphaera sp. Reveals Niche Specialization and Its Potential Role in the Human Gut

SA Shetty, NP Marathe, V Lanjekar, D Ranade… - PloS one, 2013 - journals.plos.org
With increasing number of novel bacteria being isolated from the human gut ecosystem,
there is a greater need to study their role in the gut ecosystem and their effect on the host …

Genetically encoded ATP and NAD (P) H biosensors: potential tools in metabolic engineering

S Wang, W Jiang, X Jin, Q Qi… - Critical Reviews in …, 2023 - Taylor & Francis
To date, many metabolic engineering tools and strategies have been developed, including
tools for cofactor engineering, which is a common strategy for bioproduct synthesis. Cofactor …

Revealing the Characteristics of Glucose- and Lactate-Based Chain Elongation for Caproate Production by Caproicibacterium lactatifermentans through …

H Wang, W Zhou, J Gao, C Ren, Y Xu - Msystems, 2022 - Am Soc Microbiol
Caproate, an important medium-chain fatty acid, can only be synthesized by limited bacterial
species by using ethanol, lactate, or certain saccharides. Caproicibacterium …

A redox regulatory system critical for mycobacterial survival in macrophages and biofilm development

KA Wolff, AH de la Peña, HT Nguyen, TH Pham… - PLoS …, 2015 - journals.plos.org
Survival of M. tuberculosis in host macrophages requires the eukaryotic-type protein kinase
G, PknG, but the underlying mechanism has remained unknown. Here, we show that PknG …

Reuterin disrupts Clostridioides difficile metabolism and pathogenicity through reactive oxygen species generation

MA Engevik, HA Danhof, R Shrestha… - Gut …, 2020 - Taylor & Francis
Antibiotic resistance is one of the world's greatest public health challenges and adjunct
probiotic therapies are strategies that could lessen this burden. Clostridioides difficile …

Redox-responsive repressor Rex modulates alcohol production and oxidative stress tolerance in Clostridium acetobutylicum

L Zhang, X Nie, DA Ravcheev, DA Rodionov… - Journal of …, 2014 - Am Soc Microbiol
Rex, a transcriptional repressor that modulates its DNA-binding activity in response to
NADH/NAD+ ratio, has recently been found to play a role in the solventogenic shift of …

[HTML][HTML] Effect of lactose hydrolysis on the milk-fermenting properties of Lactobacillus delbrueckii ssp. bulgaricus 2038 and Streptococcus thermophilus 1131

E Yamamoto, R Watanabe, T Ichimura, T Ishida… - Journal of Dairy …, 2021 - Elsevier
Yogurt is a well-known nutritious and probiotic food and is traditionally fermented from milk
using the symbiotic starter culture of Streptococcus thermophilus and Lactobacillus …

Mechanisms of direct inhibition of the respiratory sulfate-reduction pathway by (per) chlorate and nitrate

HK Carlson, JV Kuehl, AB Hazra, NB Justice… - The ISME …, 2015 - academic.oup.com
Abstract We investigated perchlorate (ClO4−) and chlorate (ClO3−)(collectively (per)
chlorate) in comparison with nitrate as potential inhibitors of sulfide (H2S) production by …

Streptococcus mutans NADH Oxidase Lies at the Intersection of Overlapping Regulons Controlled by Oxygen and NAD+ Levels

JL Baker, AM Derr, K Karuppaiah… - Journal of …, 2014 - Am Soc Microbiol
ABSTRACT NADH oxidase (Nox, encoded by nox) is a flavin-containing enzyme used by
the oral pathogen Streptococcus mutans to reduce diatomic oxygen to water while oxidizing …