Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

Hydrogel scaffolds for differentiation of adipose-derived stem cells

Q Huang, Y Zou, MC Arno, S Chen, T Wang… - Chemical Society …, 2017 - pubs.rsc.org
Natural extracellular matrices (ECMs) have been widely used as a support for the adhesion,
migration, differentiation, and proliferation of adipose-derived stem cells (ADSCs). However …

Electroconductive biomaterials for cardiac tissue engineering

H Esmaeili, A Patino-Guerrero, M Hasany, MO Ansari… - Acta biomaterialia, 2022 - Elsevier
Myocardial infarction (MI) is still the leading cause of mortality worldwide. The success of cell-
based therapies and tissue engineering strategies for treatment of injured myocardium have …

Combination therapy of killing diseases by injectable hydrogels: from concept to medical applications

F Poustchi, H Amani, Z Ahmadian… - Advanced …, 2021 - Wiley Online Library
The complexity of hard‐to‐treat diseases strongly undermines the therapeutic potential of
available treatment options. Therefore, a paradigm shift from monotherapy toward …

Activated ester containing polymers: opportunities and challenges for the design of functional macromolecules

A Das, P Theato - Chemical reviews, 2016 - ACS Publications
Rapidly growing demand of functional polymers in various interdisciplinary areas of
research has accentuated the need for modern synthetic tools to develop advanced …

[HTML][HTML] Drug and cell delivery for cardiac regeneration

CL Hastings, ET Roche, E Ruiz-Hernandez… - Advanced drug delivery …, 2015 - Elsevier
The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …

Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges

A Saxena, I Russo, NG Frangogiannis - Translational Research, 2016 - Elsevier
In the infarcted myocardium, necrotic cardiomyocytes release danger signals, activating an
intense inflammatory response. Inflammatory pathways play a crucial role in regulation of a …

Design principles for therapeutic angiogenic materials

PS Briquez, LE Clegg, MM Martino… - Nature Reviews …, 2016 - nature.com
Despite extensive research, pro-angiogenic drugs have failed to translate clinically, and
therapeutic angiogenesis, which has potential in the treatment of various cardiovascular …

Autophagy in SDF-1α-mediated DPSC migration and pulp regeneration

J Yang, Y Zhang, C Wan, Z Sun, S Nie, S Jian, L Zhang… - Biomaterials, 2015 - Elsevier
Critical morphological requirements for pulp regeneration are tissues replete with
vascularisation, neuron formation, and dentin deposition. Autophagy was recently shown to …

A prospective comparison of alginate-hydrogel with standard medical therapy to determine impact on functional capacity and clinical outcomes in patients with …

SD Anker, AJS Coats, G Cristian… - European heart …, 2015 - academic.oup.com
Aims AUGMENT-HF was an international, multi-centre, prospective, randomized, controlled
trial to evaluate the benefits and safety of a novel method of left ventricular (LV) modification …