A review on solubility enhancement methods for poorly water-soluble drugs
A Ainurofiq, DS Putro, DA Ramadhani… - Journal of Reports in …, 2021 - journals.lww.com
One of the most important parameters in pharmacy is drug solubility. Solubility affects the
efficacy of a drug. Drug solubility has an important role in determining the concentration of a …
efficacy of a drug. Drug solubility has an important role in determining the concentration of a …
Transdermal application of diacerin loaded-terpene enriched invasomes: an approach to augment anti-edema and nociception inhibition activity
This study aimed to formulate diacerein loaded terpene-enriched invasomes (DCN-TINV) to
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …
Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo …
The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-
loaded novasomes aiming to enhance drug corneal penetration and to improve its …
loaded novasomes aiming to enhance drug corneal penetration and to improve its …
A comprehensive review on recent nanosystems for enhancing antifungal activity of fenticonazole nitrate from different routes of administration
This review aims to comprehensively highlight the recent nanosystems enclosing
Fenticonazole nitrate (FTN) and to compare between them regarding preparation …
Fenticonazole nitrate (FTN) and to compare between them regarding preparation …
Cubogel as potential platform for glaucoma management
The aim of this work is to survey the potential of cubogel as an ocular dosage form to boost
the corneal permeability of Dorzolamide Hydrochloride DZ; an antiglaucomal drug. DZ …
the corneal permeability of Dorzolamide Hydrochloride DZ; an antiglaucomal drug. DZ …
Improving dissolution rate of carbamazepine-glutaric acid cocrystal through solubilization by excess coformer
H Yamashita, CC Sun - Pharmaceutical research, 2018 - Springer
Purpose The use of soluble cocrystals is a promising strategy for delivering poorly soluble
drugs. However, precipitation of poorly soluble crystal form during dissolution hinders the …
drugs. However, precipitation of poorly soluble crystal form during dissolution hinders the …
Engineered lecithin-based proniosomes for enhanced trans-tympanic permeation: In vitro, microbiological, ex vivo and in vivo evaluation
Otitis media is an acute illness that specifically targets the middle ear. It affects around one-
third of the pediatric population in the US. This study aimed to develop lecithin-based …
third of the pediatric population in the US. This study aimed to develop lecithin-based …
Effect of formulation variables and gamma sterilization on transcorneal permeation and stability of proniosomal gels as ocular platforms for antiglaucomal drug
This study aims to evaluate the effect of different formulation variables (surfactant type and
HLB value) adopting full factorial design (5 1. 2 1) using coacervation phase technique on in …
HLB value) adopting full factorial design (5 1. 2 1) using coacervation phase technique on in …
Application of machine learning in prediction of hydrotrope-enhanced solubilisation of indomethacin
SA Damiati, LG Martini, NW Smith, MJ Lawrence… - International Journal of …, 2017 - Elsevier
Systematic in-vitro studies have been conducted to determine the ability of a range of 10
potential hydrotropes to improve the apparent aqueous solubility of the poorly water soluble …
potential hydrotropes to improve the apparent aqueous solubility of the poorly water soluble …
[HTML][HTML] Norfloxacin mixed solvency based solid dispersions: An in-vitro and in-vivo investigation
Norfloxacin (NF) is a synthetic fluoro-quinolone molecule that is used for the treatment of
urinary tract infections. However, due to its poor aqueous solubility, it has low oral …
urinary tract infections. However, due to its poor aqueous solubility, it has low oral …