Excess iron aggravates the severity of COVID-19 infection
Abstract Coronavirus disease-19 (COVID-19) can induce severe inflammation of the lungs
and respiratory system. Severe COVID-19 is frequently associated with hyper inflammation …
and respiratory system. Severe COVID-19 is frequently associated with hyper inflammation …
COVID-19, the pandemic of the century and its impact on cardiovascular diseases
Y Zhang, M Wang, X Zhang, T Liu, P Libby… - Cardiology …, 2021 - mednexus.org
COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection likely ranks among the deadliest diseases in human history. As with other …
infection likely ranks among the deadliest diseases in human history. As with other …
Can iron chelators ameliorate viral infections?
TA Pereira, BP Espósito - BioMetals, 2024 - Springer
The redox reactivity of iron is a double-edged sword for cell functions, being either essential
or harmful depending on metal concentration and location. Deregulation of iron homeostasis …
or harmful depending on metal concentration and location. Deregulation of iron homeostasis …
Effect of iron administration on the aortic iron content and vascular calcification in phosphorus-loaded chronic kidney disease rats
M Nakanishi, A Goto, T Iwasaki, T Nakanishi, A Kuma… - BMC nephrology, 2023 - Springer
Background Cardiovascular disease (CVD) is a major cause of morbidity and mortality in
patients with chronic kidney disease (CKD) and could be related to oxidative stress …
patients with chronic kidney disease (CKD) and could be related to oxidative stress …
The hepcidin‐ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells
Elevated circulating hepcidin levels have been reported in patients with pulmonary artery
hypertension (PAH). Hepcidin has been shown to promote proliferation of human pulmonary …
hypertension (PAH). Hepcidin has been shown to promote proliferation of human pulmonary …
Long chain N3-PUFA decreases ACE2 protein levels and prevents SARS-CoV-2 cell entry
S Huang, CG Taylor, P Zahradka - International journal of molecular …, 2022 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) is a target of interest for both COVID-19 and
cardiovascular disease management. Even though lower ACE2 levels may be beneficial in …
cardiovascular disease management. Even though lower ACE2 levels may be beneficial in …
Global research trends on sepsis and septic shock during 2003–2022: A data-driven bibliometric analysis
W Han, H Guo, Z Wang, R Ding - 2024 - researchsquare.com
Background Sepsis is a major medical condition that contributes to substantial morbidity and
mortality rates worldwide. Research to better understand and manage these complex …
mortality rates worldwide. Research to better understand and manage these complex …