The full benefit of many effective medications will be achieved only if patients adhere to
prescribed treatment regimens. Unfortunately, applying terms such as “noncompliant” and …

ContextPrescription drugs are instrumental to managing and preventing chronic disease.
Recent changes in US prescription drug cost sharing could affect access to them …

Objective: The objective of this study was to evaluate the impact of medication adherence on
healthcare utilization and cost for 4 chronic conditions that are major drivers of drug …

Medical practice in the United States has changed dramatically in the last several decades,
especially with more frequent use of prescription drugs. A higher volume and better-quality …

Background A large proportion of Americans are enrolled in 3-tier pharmacy benefit plans.
We studied whether patients enrolled in such plans who receive generic or preferred brand …

Nonadherence with prescribed drug regimens is a pervasive medical problem. Multiple
variables affecting physicians and patients contribute to nonadherence, which negatively …

In this paper, we explore the role patient incentives play in slowing healthcare spending
growth. Evidence suggests that while patients do indeed respond to financial incentives …

OBJECTIVE: Little is known about patients who skip doses or otherwise avoid using their
medications because of cost. We sought to identify which elderly patients are at highest risk …

ContextWith drug spending rising rapidly for working-aged adults, many employers and
health insurance providers have changed benefits packages to encourage use of fewer or …

This book brings together a collection of articles on statistical methods relating to missing
data analysis, including multiple imputation, propensity scores, instrumental variables, and …