Organic molecules as well as metal complexes may exist as several geometric isomers1
which display distinct physical properties and chemical reactivities. A molecule containing …

Within the canonical repertoire of the amino acid involved in protein biogenesis, proline
plays a unique role as an amino acid presenting a modified backbone rather than a side …

The amide bond is one of the most important functional groups in chemistry and biology. 1
Due to the strong resonance interaction between nN and π* C O orbitals (Figure 1), 2 the …

Heterodyned femtosecond infrared two-pulse and three-pulse photon echoes of the
dipeptide acetylproline-NH2 in D2O and CDCl3 have been measured and the results have …

Cis− trans isomerization of proline-like oxazolidines and thiazolidines, denoted pseudo-
prolines, is investigated spectrophotometrically with a chymotrypsin coupled assay and by …

The [3+ 2] cycloaddition reaction between several N-metalated azomethine ylides and
nitroalkenes has been studied using AgOAc and LiClO4 as metalating reagents in the …

Conformationally constrained amino acid and dipeptide units can serve in mimics of specific
secondary structures for studying relationships between peptide conformation and biological …

Improving the accuracy of molecular mechanics force field parameters for atomistic
simulations of proteins and nucleic acids has been an ongoing effort. The availability of …

Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of
conformationally restricted analogues - ScienceDirect Skip to main contentSkip to article …

Urotensin II receptor (UT) modulators that differentiate the effects of the endogenous cyclic
peptide ligands urotensin II (UII) and urotensin II-related peptide (URP) offer potential for …