Neurons are postmitotic cells in the brain and their integrity is of central importance to avoid
neurodegeneration. Yet, the inability of self-replenishment of post-mitotic cells results in the …

All cells in organisms ranging from yeast to humans utilize iron as a cofactor or structural
element of proteins that function in diverse and critical cellular functions. However …

Background Heat shock protein family A member 5 (HSPA5), a recently identified
suppressor of ferroptosis, was reported to potentially regulating osteoarthritis. However, the …

Iron overload is associated with various pathological changes which contribute to metabolic
syndrome, many of which have been proposed to occur via damaging tissue through an …

An increase in anthropogenic activities results in metal contamination in the ecosystem
which has proven to be a major health risk in humans, as they make entry into cellular …

Levan is a high-valued polysaccharide of fructose produced by several microbial species.
These polysaccharides have been described as effective therapeutic agents in some human …

Cytokinins are adenine-based phytohormones that regulate key processes in plants, such
as cell division and differentiation, root and shoot growth, apical dominance, branching, and …

The detrimental impact on the food chain due to the overuse of rotenone is partly
responsible for alpha-synuclein (α-syn) mediated neurotoxicity. It is hypothesized that …

Abstract Introduction Neurological diseases, including Alzheimer's, Parkinson's diseases,
and brain cancers, are reportedly caused by genetic aberration and cellular malfunction …

Although copper (Cu) is an essential trace metal for cells, it can induce harmful effects as it
participates in the Fenton reaction. Involuntary exposure to Cu overload is much more …