A detailed overview of SARS-CoV-2 omicron: its sub-variants, mutations and pathophysiology, clinical characteristics, immunological landscape, immune escape, and …

S Chatterjee, M Bhattacharya, S Nag, K Dhama… - Viruses, 2023 - mdpi.com
The COVID-19 pandemic has created significant concern for everyone. Recent data from
many worldwide reports suggest that most infections are caused by the Omicron variant and …

[HTML][HTML] The novel coronavirus Disease-2019 (COVID-19): Mechanism of action, detection and recent therapeutic strategies

ES Hosseini, NR Kashani, H Nikzad, J Azadbakht… - Virology, 2020 - Elsevier
Abstract Novel coronavirus SARS-CoV-2, designated as COVID-19 by the World Health
Organization (WHO) on the February 11, 2020, is one of the highly pathogenic β …

Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

C Xu, Y Zhou, Q Xiao, B He, G Geng, Z Wang, B Cao… - Nature …, 2021 - nature.com
Competitive coevolution between microbes and viruses has led to the diversification of
CRISPR–Cas defense systems against infectious agents. By analyzing metagenomic …

Platelet‐to‐lymphocyte ratio is associated with prognosis in patients with coronavirus disease‐19

R Qu, Y Ling, Y Zhang, L Wei, X Chen… - Journal of medical …, 2020 - Wiley Online Library
Since December 2019, novel coronavirus infected pneumonia emerged in Wuhan city and
rapidly spread throughout China. In severe novel coronavirus pneumonia cases, the number …

[HTML][HTML] Coronavirus RNA proofreading: molecular basis and therapeutic targeting

F Robson, KS Khan, TK Le, C Paris, S Demirbag… - Molecular cell, 2020 - cell.com
Summary The coronavirus disease 2019 (COVID-19) that is wreaking havoc on worldwide
public health and economies has heightened awareness about the lack of effective antiviral …

[PDF][PDF] Preliminary exploration of the mechanism of Qingfei Paidu decoction against novel coronavirus pneumonia based on network pharmacology and molecular …

H Wu, JQ Wang, YW Yang, TY Li, YJ Cao… - Acta Pharmaceutica …, 2020 - elotus.org
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applied to explore the mechanism of anti-coronavirus pneumonia (coronavirus disease …

Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer

H Zhang, C Qin, C An, X Zheng, S Wen, W Chen, X Liu… - Molecular cancer, 2021 - Springer
Abstract The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and
Jennifer Doudna for the development of the Clustered regularly interspaced short …

The human coronavirus disease COVID-19: its origin, characteristics, and insights into potential drugs and its mechanisms

L Alanagreh, F Alzoughool, M Atoum - Pathogens, 2020 - mdpi.com
The emerging coronavirus disease (COVID-19) swept across the world, affecting more than
200 countries and territories. Genomic analysis suggests that the COVID-19 virus originated …

How can nanotechnology help to combat COVID-19? Opportunities and urgent need

EVR Campos, AES Pereira, JL De Oliveira… - Journal of …, 2020 - Springer
Incidents of viral outbreaks have increased at an alarming rate over the past decades. The
most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread …

Structural characterization of SARS-CoV-2: where we are, and where we need to be

G Mariano, RJ Farthing, SLM Lale-Farjat… - Frontiers in molecular …, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread in
humans in almost every country, causing the disease COVID-19. Since the start of the …