Role of telomere length in human carcinogenesis

A Tsatsakis, T Oikonomopoulou… - International …, 2023 - spandidos-publications.com
Cancer is considered the most important clinical, social and economic issue regarding
cause‑specific disability‑adjusted life years among all human pathologies. Exogenous …

[HTML][HTML] Is exposure to pesticides associated with biological aging? A systematic review and meta-analysis

S Zuo, V Sasitharan, GL Di Tanna, JM Vonk… - Ageing Research …, 2024 - Elsevier
Objective Exposure to pesticides is a risk factor for various diseases, yet its association with
biological aging remains unclear. We aimed to systematically investigate the relationship …

Leukocyte telomere length, cancer incidence and all‐cause mortality among Chinese adults: Singapore Chinese Health Study

H Samavat, HN Luu, KB Beckman, A Jin… - … journal of cancer, 2021 - Wiley Online Library
Telomeres play a key role in chromosomal maintenance and stability. To date, few studies
have investigated the association of leukocyte telomere length with risk of cancer incidence …

[HTML][HTML] Association between leukocyte telomere length and colorectal cancer risk in the Singapore Chinese health study

HN Luu, M Qi, R Wang, J Adams-Haduch… - Clinical and …, 2019 - journals.lww.com
OBJECTIVES: Telomeres and telomerase play important roles in maintaining chromosome
integrity and genomic stability. To address a lack of consensus about the association …

Telomeres, telomerase, and cancer: mechanisms, biomarkers, and therapeutics

S Shou, A Maolan, D Zhang, X Jiang, F Liu, Y Li… - … Hematology & Oncology, 2025 - Springer
Telomeres and telomerase play crucial roles in the initiation and progression of cancer. As
biomarkers, they aid in distinguishing benign from malignant tissues. Despite the promising …

[HTML][HTML] Telomere Length and Telomerase Activity as Potential Biomarkers for Gastrointestinal Cancer

C Loukopoulou, T Nikolouzakis, I Koliarakis… - …, 2024 - pmc.ncbi.nlm.nih.gov
Simple Summary Cancer affects millions worldwide, with gastrointestinal cancers being
notably common. This review explores the potential of telomeres and telomerase as …

Shorter leukocyte telomere length is associated with worse survival of patients with bladder cancer and renal cell carcinoma

X Zheng, F Wezel, A Azoitei, S Meessen, W Wang… - Cancers, 2021 - mdpi.com
Simple Summary Intrinsic telomere shortening promotes tumorigenesis in cells with
impaired DNA damage repair mechanisms, as dysfunctional telomeres lead to chromosomal …

Screening and identification of molecular targets involved in preventing gastric precancerous lesions in chronic atrophic gastritis by Qilianshupi decoction

Y Zhang, C Li, S Sun, Z Cao, J Chen… - Evidence‐Based …, 2019 - Wiley Online Library
Chronic atrophic gastritis (CAG) is a common and possibly precancerous digestive tract
disease. Development of drugs with effect of preventing precancerous lesions draws the …

Leukocyte telomere length and risk of papillary thyroid carcinoma

J Li, C An, H Zheng, T Lei, N Zhang… - The Journal of …, 2019 - academic.oup.com
Context Telomere length may contribute to predisposition to papillary thyroid cancer (PTC).
Objective To test this hypothesis, we examined the association between leukocyte telomere …

Association between leucocyte telomere length and erectile dysfunction in US adults: a secondary study based on 2001–2002 NHANES data

D Dilixiati, K Kadier, D Laihaiti, JD Lu, B Azhati… - BMJ open, 2024 - bmjopen.bmj.com
Objective We aimed to explore the association between the leucocyte telomere length (LTL)
and erectile dysfunction (ED) among a nationally representative sample of US adults …