The central dogma of gene expression propounds that DNA is transcribed to mRNA and finally gets translated into protein. Only 2–3% of the genomic DNA is transcribed to protein …
There are currently no validated biomarkers which can be used to accurately diagnose Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …
N Sideris, P Dama, S Bayraktar, T Stiff… - Cancer gene …, 2022 - nature.com
Breast cancer affects millions of women each year. Despite recent advances in targeted treatments breast cancer remains a significant threat to women's health. In recent years the …
ZS Razavi, V Tajiknia, S Majidi, M Ghandali… - Critical reviews in …, 2021 - Elsevier
Gynecologic cancers involve the female genital organs, such as the vulva, vagina, cervix, endometrium, ovaries, and fallopian tubes. The occurrence and frequency of gynecologic …
Cardiac fibrosis describes the inappropriate proliferation of cardiac fibroblasts (CFs), leading to accumulation of extracellular matrix (ECM) proteins in the cardiac muscle, which is found …
ML Idda, R Munk, K Abdelmohsen… - Wiley Interdisciplinary …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the main cause of dementia among the elderly worldwide. Despite intense efforts to develop drugs for …
Development is a complex process regulated both by genetic and epigenetic and environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key …
C Barbagallo, D Brex, A Caponnetto… - … therapy-Nucleic acids, 2018 - cell.com
Long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) contribute to the onset of many neoplasias through RNA-RNA competitive interactions; in addition, they could be …
X Liu, L Hao, D Li, L Zhu, S Hu - Genomics, proteomics and …, 2015 - academic.oup.com
With the development of genomics and bioinformatics, especially the extensive applications of high-throughput sequencing technology, more transcriptional units with little or no protein …