[HTML][HTML] Better together: circulating tumor cell clustering in metastatic cancer

E Schuster, R Taftaf, C Reduzzi, MK Albert… - Trends in cancer, 2021 - cell.com
Circulating tumor cells (CTCs) are vital components of liquid biopsies for diagnosis of
residual cancer, monitoring of therapy response, and prognosis of recurrence. Scientific …

Clinical utility of circulating tumor cells: An update

A Vasseur, N Kiavue, FC Bidard, JY Pierga… - Molecular …, 2021 - Wiley Online Library
The prognostic role of circulating tumor cells (CTCs) has been clearly demonstrated in many
types of cancer. However, their roles in diagnostic and treatment strategies remain to be …

Circulating tumor cells in precision medicine: challenges and opportunities

B Rupp, H Ball, F Wuchu, D Nagrath… - Trends in pharmacological …, 2022 - cell.com
The mutational and phenotypic landscape of tumors is dynamic, requiring constant
monitoring of cancer patients to provide the most up-to-date and effective care. Circulating …

Clinical applications of the CellSearch platform in cancer patients

S Riethdorf, L O'Flaherty, C Hille, K Pantel - Advanced drug delivery …, 2018 - Elsevier
Abstract The CellSearch® system (CS) enables standardized enrichment and enumeration
of circulating tumor cells (CTCs) that are repeatedly assessable via non-invasive “liquid …

Liquid biopsy techniques and pancreatic cancer: diagnosis, monitoring, and evaluation

K Wang, X Wang, Q Pan, B Zhao - Molecular cancer, 2023 - Springer
Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a
potential curative approach for PC, but most patients are unsuitable for operations when at …

[HTML][HTML] The detection of EpCAM+ and EpCAM–circulating tumor cells

S Wit, G Dalum, A Lenferink, AGJ Tibbe… - Scientific reports, 2015 - nature.com
EpCAM expressing circulating tumor cells, detected by CellSearch, are predictive of short
survival in several cancers and may serve as a liquid biopsy to guide therapy. Here we …

Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial

JW Valle, H Wasan, A Lopes, AC Backen… - The Lancet …, 2015 - thelancet.com
Background Cisplatin and gemcitabine is the standard first-line chemotherapy regimen for
patients with advanced biliary tract cancer; expression of VEGF and its receptors is …

Detection methods and clinical applications of circulating tumor cells in breast cancer

H Zhang, X Lin, Y Huang, M Wang, C Cen… - Frontiers in …, 2021 - frontiersin.org
Circulating Tumor Cells (CTCs) are cancer cells that split away from the primary tumor and
appear in the circulatory system as singular units or clusters, which was first reported by Dr …

Capture, release and culture of circulating tumor cells from pancreatic cancer patients using an enhanced mixing chip

W Sheng, OO Ogunwobi, T Chen, J Zhang, TJ George… - Lab on a Chip, 2014 - pubs.rsc.org
Circulating tumor cells (CTCs) from peripheral blood hold important information for cancer
diagnosis and disease monitoring. Analysis of this “liquid biopsy” holds the promise to usher …

Heterogeneity in circulating tumor cells: the relevance of the stem-cell subset

C Agnoletto, F Corrà, L Minotti, F Baldassari, F Crudele… - Cancers, 2019 - mdpi.com
The release of circulating tumor cells (CTCs) into vasculature is an early event in the
metastatic process. The analysis of CTCs in patients has recently received widespread …