PCSK9: a multi-faceted protein that is involved in cardiovascular biology

SS Sundararaman, Y Döring, EPC van Der Vorst - Biomedicines, 2021 - mdpi.com
Pro-protein convertase subtilisin/kexin type 9 (PCSK9) is secreted mostly by hepatocytes
and to a lesser extent by the intestine, pancreas, kidney, adipose tissue, and vascular cells …

Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population

I Akhlaghipour, AR Bina, MR Mogharrabi, A Fanoodi… - Human Genomics, 2022 - Springer
Diabetes is a chronic metabolic disorder that leads to the dysfunction of various tissues and
organs, including eyes, kidneys, and cardiovascular system. According to the World Health …

Osteocalcin, miR-143, and miR-145 expression in long-standing type 1 diabetes mellitus and their correlation with HbA1c

NA Hasona, AA Moneim, EA Mohammed… - Indian Journal of Clinical …, 2024 - Springer
Inadequate management and control of hyperglycemia predisposes diabetic patients to a
wide range of complications. Thus, this opens new windows for exploring and scrutinizing …

Unusual effects of PCSK9 E670G (rs505151) variation in patients with in-stent restenosis: Variable effects on restenosis risk according to concomitant chronic …

G Ozkara, EI Aslan, AB Ceviz, G Candan… - … Nucleotides & Nucleic …, 2024 - Taylor & Francis
Recent reports showing that neo-atherosclerosis formation in stented coronary artery is
characterized by the accumulation of lipid-laden macrophages within the neointima has …

Impact of PCSK9 mutations on incidences of hypercholesterolemia: A meta-analysis to infer correlation

M Singhal, R Agrawal, N Gupta - Meta Gene, 2022 - Elsevier
Background Proprotein convertase subtilisin/kexin type 9, a member of the serine protease
family, plays an important role in the regulation of plasma low density lipoprotein cholesterol …

Analysis of the Correlation between FH and PCSK9 and APOB Gene Mutations in Han and Mongolian Populations of the Hulunbuir.

W Gao, Y Ren, Z Zheng, H Sun… - Clinical Laboratory, 2024 - search.ebscohost.com
Background: The goal of the study was to provide an individual and precise genetic and
molecular biological basis for the early prevention, diagnosis, and treatment of local FH by …

[PDF][PDF] PCSK9: A Multi-Faceted Protein That Is Involved in Cardiovascular Biology. Biomedicines 2021, 9, 793

SS Sundararaman, Y Döring, EPC van der Vorst - 2021 - publications.rwth-aachen.de
Pro-protein convertase subtilisin/kexin type 9 (PCSK9) is secreted mostly by hepatocytes
and to a lesser extent by the intestine, pancreas, kidney, adipose tissue, and vascular cells …