Seven challenges in the multiscale modeling of multicellular tissues
AG Fletcher, JM Osborne - WIREs mechanisms of disease, 2022 - Wiley Online Library
The growth and dynamics of multicellular tissues involve tightly regulated and coordinated
morphogenetic cell behaviors, such as shape changes, movement, and division, which are …
morphogenetic cell behaviors, such as shape changes, movement, and division, which are …
Multiscale modelling of desquamation in the interfollicular epidermis
Maintenance of epidermal thickness is critical to the barrier function of the skin. Decreased
tissue thickness, specifically in the stratum corneum (the outermost layer of the tissue) …
tissue thickness, specifically in the stratum corneum (the outermost layer of the tissue) …
Cooperative success in epithelial public goods games
Cancer cells obtain mutations which rely on the production of diffusible growth factors to
confer a fitness benefit. These mutations can be considered cooperative, and studied as …
confer a fitness benefit. These mutations can be considered cooperative, and studied as …
Developing hybrid continuum-discrete models for the study of environment-metabolism feedback in cellular systems
CGM Johnson - 2022 - wrap.warwick.ac.uk
Cellular systems are ubiquitous in nature. They form tissues and multicellular organisms
where the cell interactions form complex biological structures. Understanding cell system …
where the cell interactions form complex biological structures. Understanding cell system …