Reperfusion of ischemic myocardium is necessary to salvage tissue from eventual death.
However, reperfusion after even brief periods of ischemia is associated with pathologic …

Administration of nitric oxide (NO), NO donors or drugs that enhance NO realease (statins,
calcium antagonists, ACE-inhibitors, dexamethasone) prior to ischemia protects the …

The widespread introduction of fibrinolytics and recently also PTCA in the treatment of
myocardial infarction has changed the picture of modern cardiology. But this therapy also …

Over the past decade, an enormous number of studies (> 100) have focused on the role of
nitric oxide (NO) in myocardial ischemia. It is important to distinguish the function of NO in …

Over the past 5 years there has been an explosion of new information on the physiological
and pathophysiological roles of NO within the heart as in other organ systems. In this review …

Our review aims to examine the cellular and molecular mechanisms of cardiovascular
protection of green tea polyphenols, particularly epigallocatechin gallate (EGCG), which …

Caffeic acid phenethyl ester (CAPE) could ameliorate myocardial ischemia/reperfusion
injury (MIRI) by various mechanisms, but there hadn't been any reports on that CAPE could …

Nitrite has emerged as an endogenous signaling molecule with potential therapeutic
implications for cardiovascular disease. Steady-state levels of nitrite are derived in part from …

Nitric oxide (NO) is known to be an important endogenous modulator of leukocyte-
endothelial cell interactions within the microcirculation. We examined leukocyte rolling and …

Complex paracrine interactions exist between endothelial cells and cardiac myocytes in the
heart. Cardiac endothelial cells release (or metabolize) several diffusible agents (eg, nitric …