Introduction Irisin is a myokine/adipokine induced by the exercise in mice and humans,
which is proposed to induce “browning” of white adipose tissue, its primary target, thus …

Homeostasis of energy is regulated by genetic factors, food intake, and energy expenditure.
When energy input is greater than expenditure, the balance is positive, which can lead to …

Context: Irisin, a recently identified hormone, has been proposed to regulate energy
homeostasis and obesity in mice. Whether irisin levels are associated with risk of the …

Key points Considerable controversy exists regarding the role of irisin, a putative exercise‐
induced myokine, in human metabolism. We therefore studied irisin and its precursor Fndc5 …

Background: Irisin is a recently identified exercise-induced myokine suggested to induce
browning of white adipocytes. Deficiency of myostatin, and thus stimulation of muscle …

Background Irisin, a recently discovered myokine, has been shown to induce browning of
white adipose tissue, enhancing energy expenditure and mediating some of the beneficial …

Appetite and body weight regulation are controlled by the central nervous system (CNS) in a
rather complicated manner. The human brain plays a central role in integrating internal and …

Purpose: The prevalence of obesity as a health problem is known in all over the world, as
well as diseases associated with obesity, including insulin resistance, metabolic syndrome …

Objective Irisin is a recently discovered myokine proposed to increase thermogenesis-
related energy expenditure and improve metabolism. We aimed to comparatively evaluate …

Context: The myokine irisin may increase energy expenditure and affect metabolism.
Objective: The objective of the study was to elucidate predictors of irisin and study whether …