Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Comparison of GEANT4 very low energy cross section models with experimental data in water

S Incerti, A Ivanchenko, M Karamitros… - Medical …, 2010 - Wiley Online Library
Purpose: Thegeant4 general‐purpose Monte Carlo simulation toolkit is able to simulate
physical interaction processes of electrons, hydrogen and helium atoms with charge states …

Comprehensive analysis of proton range uncertainties related to patient stopping-power-ratio estimation using the stoichiometric calibration

M Yang, XR Zhu, PC Park, U Titt… - Physics in Medicine …, 2012 - iopscience.iop.org
The purpose of this study was to analyze factors affecting proton stopping-power-ratio (SPR)
estimations and range uncertainties in proton therapy planning using the standard …

Modelling Cellular Response to Ionizing Radiation: Mechanistic, Semi-Mechanistic, and Phenomenological Approaches–a Historical Perspective

R Taleei, S Rahmanian, H Nikjoo - Radiation Research, 2024 - meridian.allenpress.com
Radiation research is a multidisciplinary field, and among its many branches, mathematical
and computational modelers have played a significant role in advancing boundaries of …

The IAEA stopping power database, following the trends in stopping power of ions in matter

CC Montanari, P Dimitriou - Nuclear Instruments and Methods in Physics …, 2017 - Elsevier
The aim of this work is to present an overview of the state of art of the energy loss of ions in
matter, based on the new developments in the stopping power database of the International …

Validation of recent Geant4 physics models for application in carbon ion therapy

A Lechner, VN Ivanchenko, J Knobloch - Nuclear Instruments and Methods …, 2010 - Elsevier
Cancer treatment with energetic carbon ions has distinct advantages over proton or photon
irradiation. In this paper we present a simulation model integrated into the Geant4 Monte …

Optimized I-values for use with the Bragg additivity rule and their impact on proton stopping power and range uncertainty

E Bär, P Andreo, A Lalonde, G Royle… - Physics in Medicine & …, 2018 - iopscience.iop.org
Novel imaging modalities can improve the estimation of patient elemental compositions for
particle treatment planning. The mean excitation energy (I-value) is a main contributor to the …

[HTML][HTML] Efficient computational modeling of electronic stopping power of organic polymers for proton therapy optimization

F Matias, TF Silva, NE Koval, JJN Pereira… - Scientific Reports, 2024 - nature.com
This comprehensive study delves into the intricate interplay between protons and organic
polymers, offering insights into proton therapy in cancer treatment. Focusing on the influence …

Application of a simple DNA damage model developed for electrons to proton irradiation

Y Matsuya, T Kai, A Parisi, Y Yoshii… - Physics in Medicine & …, 2022 - iopscience.iop.org
Proton beam therapy allows irradiating tumor volumes with reduced side effects on normal
tissues with respect to conventional x-ray radiotherapy. Biological effects such as cell killing …

-Shell Core-Electron Excitations in Electronic Stopping of Protons in Water from First Principles

Y Yao, DC Yost, Y Kanai - Physical Review Letters, 2019 - APS
Understanding the role of core-electron excitation in liquid water under proton irradiation
has become important due to the growing use of proton beams in radiation oncology. Using …