Alopecia areata: an update on etiopathogenesis, diagnosis, and management

C Zhou, X Li, C Wang, J Zhang - Clinical Reviews in Allergy & …, 2021 - Springer
Alopecia areata (AA) is a common chronic tissue-specific autoimmune disease, resulting in
hair loss, that affects up to 2% of the general population. The exact pathobiology of AA has …

The burden of alopecia areata: a scoping review focusing on quality of life, mental health and work productivity

A Muntyanu, S Gabrielli, J Donovan… - Journal of the …, 2023 - Wiley Online Library
Alopecia areata (AA) is a common inflammatory autoimmune disease of the hair which can
have a significant negative impact on quality of life (QoL), mental health and productivity …

Two phase 3 trials of baricitinib for alopecia areata

B King, M Ohyama, O Kwon, A Zlotogorski… - … England Journal of …, 2022 - Mass Medical Soc
Background Alopecia areata is an autoimmune condition characterized by rapid hair loss in
the scalp, eyebrows, and eyelashes, for which treatments are limited. Baricitinib, an oral …

Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata: a randomised, double-blind, multicentre, phase 2b–3 trial

B King, X Zhang, WG Harcha, JC Szepietowski… - The Lancet, 2023 - thelancet.com
Background Alopecia areata is characterised by non-scarring loss of scalp, face, or body
hair. We investigated the efficacy and safety of ritlecitinib, an oral, selective dual JAK3/TEC …

[HTML][HTML] Efficacy and safety of the oral Janus kinase inhibitor baricitinib in the treatment of adults with alopecia areata: phase 2 results from a randomized controlled …

B King, J Ko, S Forman, M Ohyama… - Journal of the American …, 2021 - Elsevier
Background There are no treatments approved by the Food and Drug Administration for
alopecia areata. Objective To evaluate the efficacy and safety of baricitinib in patients with≥ …

Alopecia areata: Current understanding of the pathophysiology and update on therapeutic approaches, featuring the Japanese Dermatological Association guidelines

M Fukuyama, T Ito, M Ohyama - The Journal of dermatology, 2022 - Wiley Online Library
Alopecia areata (AA) is a relatively common nonscarring hairloss disease characterized by
an autoimmune response to anagen hair follicles (HFs). Accumulated evidence suggests …

“'You lose your hair, what's the big deal?' I was so embarrassed, I was so self-conscious, I was so depressed:” a qualitative interview study to understand the …

NVJ Aldhouse, H Kitchen, S Knight, J Macey… - Journal of Patient …, 2020 - Springer
Background Alopecia areata (AA) is characterized by hair loss that can affect the scalp and
body. This study describes the psychosocial burden of AA. Methods Participants diagnosed …

Defining severity in alopecia areata: current perspectives and a multidimensional framework

BA King, MM Senna, M Ohyama, A Tosti… - Dermatology and …, 2022 - Springer
Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss. As a
clinically heterogeneous disease, various classification systems have evolved for defining its …

[HTML][HTML] Development of the alopecia areata scale for clinical use: results of an academic–industry collaborative effort

BA King, NA Mesinkovska, B Craiglow… - Journal of the American …, 2022 - Elsevier
Background The current classification for Alopecia Areata (AA) does not provide a consistent
assessment of disease severity. Objective To develop an AA severity scale based on expert …

Systematic review of newer agents for the management of alopecia areata in adults: Janus kinase inhibitors, biologics and phosphodiesterase‐4 inhibitors

AK Gupta, T Wang, S Polla Ravi… - Journal of the …, 2023 - Wiley Online Library
Management options for moderate‐to‐severe alopecia areata (AA) are limited owing to a
lack of safe and effective treatments suitable for long‐term use. However, newer agents …