Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions
Z Megyesfalvi, CM Gay, H Popper… - CA: a cancer journal …, 2023 - Wiley Online Library
Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity.
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
[HTML][HTML] Re-examining prophylactic cranial irradiation in small cell lung cancer: a systematic review and meta-analysis
Background Patients with small cell lung cancer (SCLC) are at high risk for brain
metastases. Prophylactic cranial irradiation (PCI) is recommended in this population to …
metastases. Prophylactic cranial irradiation (PCI) is recommended in this population to …
Benefits of prophylactic cranial irradiation in the MRI era for patients with limited stage small cell lung cancer
C Qi, W Li, H Li, F Wen, L Zhou, X Sun, H Yu - Frontiers in Oncology, 2022 - frontiersin.org
Purpose Previous studies have shown that prophylactic cranial irradiation (PCI) can improve
the survival of patients with limited-stage small cell lung cancer (LS-SCLC). PCI is …
the survival of patients with limited-stage small cell lung cancer (LS-SCLC). PCI is …
Utility of prophylactic cranial irradiation for limited stage small cell lung cancer in the modern era with magnetic resonance imaging surveillance
S Ghanta, A Keller, JL Rodríguez-López, A Patel… - Clinical Oncology, 2021 - Elsevier
Aims To retrospectively analyse the impact of prophylactic cranial irradiation (PCI) on
survival and intracranial progression in patients with limited stage small cell lung cancer (LS …
survival and intracranial progression in patients with limited stage small cell lung cancer (LS …
[HTML][HTML] The overall survival impact of prophylactic cranial irradiation in limited-stage small-cell lung cancer: A systematic review and meta-analysis
ML Tomassen, J Pomp, J van der Stap… - Clinical and translational …, 2022 - Elsevier
Background Prophylactic cranial irradiation (PCI) for limited-stage small-cell lung cancer (LS-
SCLC) patients has become more controversial. Since the publication of the systematic …
SCLC) patients has become more controversial. Since the publication of the systematic …
[HTML][HTML] Prophylactic cranial irradiation in patients with small cell lung cancer in The Netherlands: a population-based study
ML Tomassen, MJ Aarts, M Peters, A van Lindert… - Clinical and translational …, 2021 - Elsevier
Introduction Controversy has arisen regarding the benefit of prophylactic cranial irradiation
(PCI) in patients with small cell lung cancer (SCLC), particularly since the 2017 Takahashi …
(PCI) in patients with small cell lung cancer (SCLC), particularly since the 2017 Takahashi …
Survival benefit of prophylactic cranial irradiation in limited-stage small-cell lung cancer in modern magnetic resonance imaging staging: a systematic review and meta …
J Liu, B Shen, Y Yang, J Guo, W Ren, Q Zhou… - Acta …, 2023 - Taylor & Francis
Background The use of prophylactic cranial irradiation (PCI) in patients suffering from limited-
stage small-cell lung cancer (LS-SCLC) remains controversial in modern brain magnetic …
stage small-cell lung cancer (LS-SCLC) remains controversial in modern brain magnetic …
Pamiparib as consolidation treatment after concurrent chemoradiotherapy of limited-stage small cell lung cancer: a single-arm, open-label phase 2 trial
J Mao, J Ni, L Chu, X Chu, D Xu, X Yang, Z Zhu - Radiation Oncology, 2024 - Springer
Background Small cell lung cancer (SCLC) is highly invasive with poor prognosis, and its
treatment has historically been hindered due to the absence of targetable driver genomic …
treatment has historically been hindered due to the absence of targetable driver genomic …
Construction of brain metastasis prediction model and optimization of prophylactic cranial irradiation selection for limited-stage small-cell lung cancer
Q Hou, B Sun, N Yao, Y Liang, X Cao, L Wei, J Cao - Cancers, 2022 - mdpi.com
Simple Summary The brain is a common metastasis site of small-cell lung cancer (SCLC),
and up to 50% of SCLC patients are at risk of brain metastasis (BM) within 2 years …
and up to 50% of SCLC patients are at risk of brain metastasis (BM) within 2 years …
[HTML][HTML] Limited-stage small cell lung cancer: outcomes associated with prophylactic cranial irradiation over a 20-year period at the Princess Margaret Cancer Centre
Background & purpose Prophylactic cranial irradiation (PCI) is recommended for limited-
stage small-cell lung cancer (LS-SCLC) patients with good response to concurrent …
stage small-cell lung cancer (LS-SCLC) patients with good response to concurrent …