The most fundamental feature of cellular form is size, which sets the scale of all cell
biological processes. Growth, form, and function are all necessarily linked in cell biology, but …

The human retinoblastoma (RB 1) protein is a tumor suppressor that negatively regulates
cell cycle progression through its interaction with members of the E2F/DP family of …

Polyploidy is a key mechanism of genome evolution and speciation, particularly in plants.
Many aspects of polyploidy have been elucidated with the tools that have become available …

Porphyra umbilicalis (laver) belongs to an ancient group of red algae (Bangiophyceae), is
harvested for human food, and thrives in the harsh conditions of the upper intertidal zone …

Depending on cell type, environmental inputs, and disease, the cells in the human body can
have widely different sizes. In recent years, it has become clear that cell size is a major …

Cell proliferation is a central process in tissue development, homeostasis, and disease, yet
how proliferation is regulated in the tissue context remains poorly understood. Here, we …

How eukaryotic cells assess and maintain sizes specific for their species and cell type
remains unclear. We show that in the Arabidopsis shoot stem cell niche, cell size variability …

Patterning of a multicellular body plan involves a coordinated set of developmental
processes that includes cell division, morphogenesis, and cellular differentiation. These …

Although it has long been clear that cells actively regulate their size, the molecular
mechanisms underlying this regulation have remained poorly understood. In budding yeast …

The genetic control of the characteristic cell sizes of different species and tissues is a long-
standing enigma. Plants are convenient for studying this question in a multicellular context …