Sleep disturbance is increasingly recognized as an important, but understudied, mechanism
in the complex and multi-factorial causation of the symptoms and functional disability …

Conditioned place preference (CPP) continues to be one of the most popular models to
study the motivational effects of drugs and non‐drug treatments in experimental animals …

Circadian rhythms influence most of our life activities, notably getting up and going to sleep
every day. The new edition of this book delves into the mechanisms surrounding how these …

This review consolidates research employing human correlational and experimental work
across brain and body with experimental animal models to provide a more complete …

The circadian system has pronounced influence on learning and memory, manifesting as
marked changes in memory acquisition and recall across the day. From a mechanistic …

Background Circadian disruptions through frequent transmeridian travel, rotating shift work,
and poor sleep hygiene are associated with an array of physical and mental health …

Existing literature on reward motivation pays scant attention to the fact that reward potential
of the environment varies dramatically with the light/dark cycle. Evolution, by contrast, treats …

Circadian clocks evolved under conditions of environmental variation, primarily alternating
light dark cycles, to enable organisms to anticipate daily environmental events and …

Circadian rhythms are endogenous and need to be continuously entrained (synchronized)
with the environment. Entrainment includes both coupling internal oscillators to external …

Time of day can influence cocaine-seeking behavior in rats, and this influence may depend
on the suprachiasmatic nucleus (SCN). We used western blots to measure expression of …