Fatty liver diseases can result from common metabolic diseases, as well as from xenobiotic
exposure and excessive alcohol use, all of which have been shown to exert toxic effects on …

Based on the assumption that characterizing the history of a disease will help in improving
practice while offering a clue to research, this article aims at reviewing the history of …

Non-alcoholic fatty liver disease (NAFLD) has become the most common liver disorder of
our times. Simple steatosis, a seemingly innocent manifestation of NAFLD, may progress …

The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing all around the
world and it may become the primary cause of terminal liver disease in adults and children …

In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

Hepatic steatosis is often associated with insulin resistance and obesity and can lead to
steatohepatitis and cirrhosis. In this study, we have demonstrated that hormone-sensitive …

The decrease in adiponectin levels are negatively correlated with chronic subclinical
inflammation markers in obesity. The hypertrophic adipocytes cause obesity-linked insulin …

Background: The mechanisms of progression from fatty liver to steatohepatitis and cirrhosis
are not well elucidated. Mitochondrial dysfunction represents a key factor in the progression …

The uncoupling proteins (UCPs) are attracting an increased interest as potential therapeutic
targets in a number of important diseases. UCP2 is expressed in several tissues, but its …

In the liver, adiponectin regulates both glucose and lipid metabolism and exerts an insulin-
sensitizing effect. The binding of adiponectin with its specific receptors induces the activation …