Self-assembled mRNA vaccines

J Kim, Y Eygeris, M Gupta, G Sahay - Advanced drug delivery reviews, 2021 - Elsevier
Abstract mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-
19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology …

Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies

FM Kashkooli, M Soltani, M Souri - Journal of controlled release, 2020 - Elsevier
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

Chloroplast-selective gene delivery and expression in planta using chitosan-complexed single-walled carbon nanotube carriers

SY Kwak, TTS Lew, CJ Sweeney, VB Koman… - Nature …, 2019 - nature.com
Plant genetic engineering is an important tool used in current efforts in crop improvement,
pharmaceutical product biosynthesis and sustainable agriculture. However, conventional …

High aspect ratio nanomaterials enable delivery of functional genetic material without DNA integration in mature plants

GS Demirer, H Zhang, JL Matos, NS Goh… - Nature …, 2019 - nature.com
Genetic engineering of plants is at the core of sustainability efforts, natural product synthesis
and crop engineering. The plant cell wall is a barrier that limits the ease and throughput of …

Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology

N Bertrand, J Wu, X Xu, N Kamaly… - Advanced drug delivery …, 2014 - Elsevier
Cancer nanotherapeutics are progressing at a steady rate; research and development in the
field has experienced an exponential growth since early 2000's. The path to the …

Carbon nanotubes: a novel material for multifaceted applications in human healthcare

S Kumar, R Rani, N Dilbaghi, K Tankeshwar… - Chemical society …, 2017 - pubs.rsc.org
Remarkable advances have been achieved in modern material technology, especially in
device fabrication, and these have facilitated the use of diverse materials in various …

Carbon nanotubes in biomedical applications: factors, mechanisms, and remedies of toxicity: miniperspective

R Alshehri, AM Ilyas, A Hasan, A Arnaout… - Journal of medicinal …, 2016 - ACS Publications
Carbon nanotubes (CNTs) represent one of the most studied allotropes of carbon. The
unique physicochemical properties of CNTs make them among prime candidates for …

Chemical basis of interactions between engineered nanoparticles and biological systems

Q Mu, G Jiang, L Chen, H Zhou, D Fourches… - Chemical …, 2014 - ACS Publications
As defined by the European Commission, a nanomaterial is a natural, an incidental, or a
manufactured material containing particles in an unbound state or as an aggregate or …

Aptamers from cell-based selection for bioanalytical applications

W Tan, MJ Donovan, J Jiang - Chemical reviews, 2013 - ACS Publications
Nucleic acids are the foundation of life. Specific sequences translate certain genetic traits,
protein expression, and, ultimately, cellular function. Yet, nucleic acids not only store genetic …

Carbon nanocarriers deliver siRNA to intact plant cells for efficient gene knockdown

GS Demirer, H Zhang, NS Goh, RL Pinals, R Chang… - Science …, 2020 - science.org
Posttranscriptional gene silencing (PTGS) is a powerful tool to understand and control plant
metabolic pathways, which is central to plant biotechnology. PTGS is commonly …