Publisher Summary Cancer progression and metastasis are complex processes associated
with multiple and highly organized sequential steps that are both well coordinated and …

Calmodulin (CaM) is the principal Ca2+ sensor protein in all eukaryotic cells, that upon
binding to target proteins transduces signals encoded by global or subcellular-specific …

An assay was developed to study inflammation-related immune responses of food
compounds on monocytes and macrophages derived from THP-1 cell line. First strategy …

Chemoresistance in pancreatic cancer cells may be caused by the expansion of inherently
resistant cancer cells or by the adaptive plasticity of initially sensitive cancer cells. We …

Kawasaki disease (KD) is a pediatric vasculitis that damages the coronary arteries in 25% of
untreated and approximately 5% of treated children. Epidemiologic data suggest that KD is …

Objective Advanced glycation end products (AGEs) and endothelial progenitor cells (EPCs)
play divergent roles in the process of atherosclerosis. We investigated the effects of AGE …

The hyaluronan receptor LYVE-1 is selectively expressed in the endothelium of lymphatic
capillaries, where it has been proposed to function in hyaluronan clearance and hyaluronan …

Substantial data from clinical trials and epidemiological studies show promising results for
use of statins in many cancers, including mammary carcinoma. Breast tumor primarily …

Tanshinones are the major bioactive compounds of Salvia miltiorrhiza Bunge (Danshen)
roots, which are used in many therapeutic remedies in Chinese traditional medicine. We …

CaMKII has been shown to be activated during different cardiac pathological processes, and
CaMKII-dependent mechanisms contribute to pathological cardiac remodeling, cardiac …