Language in autism: domains, profiles and co-occurring conditions

J Schaeffer, M Abd El-Raziq, E Castroviejo… - Journal of Neural …, 2023 - Springer
This article reviews the current knowledge state on pragmatic and structural language
abilities in autism and their potential relation to extralinguistic abilities and autistic traits. The …

[HTML][HTML] Validation strategies for subtypes in psychiatry: A systematic review of research on autism spectrum disorder

JAA van Rentergem, MK Deserno, HM Geurts - Clinical Psychology …, 2021 - Elsevier
Heterogeneity within autism spectrum disorder (ASD) is recognized as a challenge to both
biological and psychological research, as well as clinical practice. To reduce unexplained …

Building a knowledge graph to enable precision medicine

P Chandak, K Huang, M Zitnik - Scientific Data, 2023 - nature.com
Developing personalized diagnostic strategies and targeted treatments requires a deep
understanding of disease biology and the ability to dissect the relationship between …

Being versus appearing socially uninterested: Challenging assumptions about social motivation in autism

VK Jaswal, N Akhtar - Behavioral and Brain Sciences, 2019 - cambridge.org
Progress in psychological science can be limited by a number of factors, not least of which
are the starting assumptions of scientists themselves. We believe that some influential …

Contrastive machine learning reveals the structure of neuroanatomical variation within autism

A Aglinskas, JK Hartshorne, S Anzellotti - Science, 2022 - science.org
Autism spectrum disorder (ASD) is highly heterogeneous. Identifying systematic individual
differences in neuroanatomy could inform diagnosis and personalized interventions. The …

Developmental trajectories of symptom severity and adaptive functioning in an inception cohort of preschool children with autism spectrum disorder

P Szatmari, S Georgiades, E Duku, TA Bennett… - JAMA …, 2015 - jamanetwork.com
Importance Symptom severity and adaptive functioning are fundamental domains of the
autism spectrum disorder (ASD) phenotype. To date, the longitudinal association between …

Subtyping attention-deficit/hyperactivity disorder using temperament dimensions: toward biologically based nosologic criteria

SL Karalunas, D Fair, ED Musser, K Aykes… - JAMA …, 2014 - jamanetwork.com
Importance Psychiatric nosology is limited by behavioral and biological heterogeneity within
existing disorder categories. The imprecise nature of current nosologic distinctions limits …

A data-driven approach in an unbiased sample reveals equivalent sex ratio of autism spectrum disorder–associated impairment in early childhood

CA Burrows, RL Grzadzinski, K Donovan… - Biological …, 2022 - Elsevier
Background Sex differences in the prevalence of neurodevelopmental disorders are
particularly evident in autism spectrum disorder (ASD). Heterogeneous symptom …

Heterogeneity within autism spectrum disorders: what have we learned from neuroimaging studies?

RK Lenroot, PK Yeung - Frontiers in human neuroscience, 2013 - frontiersin.org
Autism spectrum disorders (ASD) display significant heterogeneity. Although most
neuroimaging studies in ASD have been designed to identify commonalities among affected …

Candidate biomarkers in children with autism spectrum disorder: a review of MRI studies

D Li, HO Karnath, X Xu - Neuroscience bulletin, 2017 - Springer
Searching for effective biomarkers is one of the most challenging tasks in the research field
of Autism Spectrum Disorder (ASD). Magnetic resonance imaging (MRI) provides a non …